an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate

(2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA

5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

(2Z,4Z)-2-hydroxyhexa-2,4-dienoate

(S)-4-hydroxy-2-oxohexanoate

(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate

3,5-dihydro-4H-imidazol-4-one

4-aminoimidazole

5-aminoimidazole-4-carboxylate

5-ureidoimidazole-4-carboxylate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

3-amino-1-hydroxyacetone 1-phosphate

N-acetyl-α-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol

pseudouridine

enol-phenylpyruvate

ammonia

(4-hydroxyphenyl)acetate

S-methyl-5-thio-α-D-ribose 1-phosphate

anthranilate

N-(5-phosphoribosyl)-anthranilate

2-amino-3-carboxymuconate-6-semialdehyde

quinolinate

2-dehydropantoate

7-epicholate

3α,12α-dihydroxy-7-oxo-5β-cholan-24-oate

3-methyl-2-oxobutanoate

2-iminoacetate

1,6-anhydro-N-acetyl-β-muramate

N-acetyl-D-muramate 6-phosphate

3-hydroxy-5- oxohexanoyl-CoA

3-hydroxy-5-oxohexanoate

dihydrophloroglucinol

phloroglucinol

pyrogallol

1,2,3,5-tetrahydroxybenzene

gallate

acetoacetate

(S)-5-amino-3-oxohexanoate

(3S,5S)-3,5-diaminohexanoate

butanoyl phosphate

(L-threonylcarbamoyl)adenylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

succinate semialdehyde

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

4-acetamidobutanal

4-acetamidobutanoate

N²-succinyl-L-glutamate 5-semialdehyde

N²-succinylglutamate

2-oleoylglycerol

4-amino-4-deoxychorismate

β-nicotinate D-ribonucleotide

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

L-β-lysine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

hypotaurine

4-methyl-3-oxoadipate

hydroxypyruvate

histidinal

histidinol

poly(ribitol phosphate)

O-D-alanyl-poly(ribitol phosphate)

pseudouridine 5'-phosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

DNA without lesion

3-phosphooxypyruvate

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

4-phosphooxy-L-threonine

4-aminobutanoate

(R)-pantothenate

1-deoxy-L-glycero-tetrulose 4-phosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(D-ribitylamino)uracil

4-pyridoxolactone

oxaloacetate

CDP-glycerol

ManNAc-GlcNAc-PP-undecaprenol

citrate

oxalosuccinate

hydrogen selenide

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

3-dehydroshikimate

5-enolpyruvoyl-shikimate 3-phosphate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

phosphoenolpyruvate

O-acetyl-L-serine

S-methyl-5'-thioadenosine

S-methyl-5'-thioinosine

S-Inosyl-L-homocysteine

nicotinate adenine dinucleotide

α-D-glucosamine 1-phosphate

glycerone phosphate

γ-L-glutamyl 5-phosphate

4'-phosphopantetheine

acetyl phosphate

xanthine

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

hydrogen peroxide

prenyl diphosphate

H₂O

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

shikimate

shikimate 3-phosphate

coproporphyrinogen III

CO₂

hydrogensulfite

sulfite

molybdate

hydrogencarbonate

thiosulfate

phosphate

triphosphate

diphosphate

Na⁺

H⁺

ammonium

Co²⁺

Fe²⁺

trimethyl sulfonium

dimethyl sulfide

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

taurine

sulfoacetaldehyde

2-sulfinoacetaldehyde

methanethiol

(2Z)-2-aminobut-2-enoate

2-iminopropanoate

2-aminoprop-2-enoate

cadaverine

butan-1-ol

2,3-dihydroxybenzoate

3α,7α,12β-trihydroxy-5β-cholan-24-oate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

9α-hydroxyandrosta-1,4-diene-3,17-dione

androst-4-ene-3,17-dione

androsta-1,4-diene-3,17-dione

3-dehydrocholate

isocholate

glycocholate

cholate

(indol-3-yl)acetate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

fluoroacetaldehyde

fluoroacetate

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

nicotinamide

(R)-pantoate

acetate

(S)-1-pyrroline-5-carboxylate

L-aspartyl-4-phosphate

O-acetyl-L-homoserine

3-phospho-L-serine

N-formimino-glycine

L-methionine

L-proline

L-leucine

L-tryptophan

glycine

L-selenocysteine

L-alanine

L-phenylalanine

L-cysteine

L,L-diaminopimelate

L-histidine

L-threonine

L-tyrosine

L-cystathionine

L-serine

L-aspartate

L-asparagine

L-lysine

L-glutamine

L-glutamate

O-succinyl-L-homoserine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

S-sulfo-L-cysteine

L-homocysteine

L-glutamate-5-semialdehyde

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

meso-diaminopimelate

β-alanine

D-glutamate

D-aspartate

D-alanine

cis-aconitate

D-threo-isocitrate

chorismate

fumarate

succinate

4-hydroxybutanoate

(R)-glycerate

(R)-lactate

pyruvate

formate

butanoate

decanoate

octanoate

3-oxoadipate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

glyoxylate

4-(methylsulfanyl)-2-oxobutanoate

2-oxoglutarate

salicylate

benzoate

4-aminobenzoate

palmitate

pristanate

(15Z)-tetracosenoate

oleate

phytenate

apo-4'-lycopenoate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

linoleate

Gro-P-ManNAc-GlcNAc-PP-undecaprenol

salicylaldehyde

aldehydo-D-ribose

α-D-ribofuranose

β-D-ribofuranose

phytenal

1-propanal

1-octanal

acetaldehyde

butan-1-al

benzaldehyde

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

4-phospho-D-erythronate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

α-D-mannose 1-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-glucopyranose 1-phosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

ADP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

a peptidoglycan dimer (E. faecium, tetrapeptide)

a peptidoglycan dimer (mycobacteria)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (E. faeciums)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

a peptidoglycan with D,D cross-link (S. aureus)

a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

a peptidoglycan dimer (meso-diaminopimelate containing)

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

D-glyceraldehyde 3-phosphate

β-D-fructofuranose

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-β-D-glucosamine

sucrose

(S)-3-aminobutanoyl-CoA

4-hydroxybutanoyl-CoA

trans-caffeoyl-CoA

trans-feruloyl-CoA

2-methylacetoacetyl-CoA

succinyl-CoA

CoA-disulfide

linoleoyl-CoA

α-linolenoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

acetyl-CoA

3'-dephospho-CoA

crotonyl-CoA

(2E)-dec-2-enoyl-CoA

phytenoyl-CoA

oleoyl-CoA

4-methyl-3-oxoadipyl-CoA

3-oxoadipyl-CoA

3-oxohexanoyl-CoA

3-oxooctanoyl-CoA

3-oxodecanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

propanoyl-CoA

butanoyl-CoA

palmitoyl-CoA

(Z)-15-tetracosenoyl-CoA

pristanoyl-CoA

decanoyl-CoA

octanoyl-CoA

geranyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

trans,octacis-decaprenyl phosphate

(2E,6E)-farnesyl diphosphate

apo-4'-lycopenal

dioleoyl phosphatidate

1-oleoyl-2-lyso-glycerone phosphate

1-oleoyl-sn-glycerol 3-phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

all-trans-heptaprenyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

8-hydroxypurine

6,8-dihydroxypurine

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

phenol

4-methylphenol

guanine

adenine

purine

hypoxanthine

dIMP

dITP

dGTP

XTP

ITP

GTP

ATP

GDP

ADP

AMP

XMP

IMP

GMP

2'-deoxyinosine

2'-deoxyadenosine

2'-deoxyguanosine

inosine

xanthosine

guanosine

adenosine

FMN

riboflavin

FAD

FMNH₂

FADH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

(7,8-dihydropterin-6-yl)methyl diphosphate

molybdopterin adenine dinucleotide

molybdopterin

cyclic pyranopterin phosphate

MoO₂-molybdopterin cofactor

7,8-dihydropteroate

7,8-dihydrofolate monoglutamate

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

dUDP

dCTP

dTTP

CDP

dCDP

dTDP

dCMP

dUTP

uracil

dUMP

dTMP

UTP

UDP

CTP

thymine

CMP

UMP

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

preQ₁

sirohydrochlorin

cobyrinate

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-1

precorrin-2

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-AMP

pppGpp

ppGpp

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

NAD⁺

NADP⁺

NADH

NADPH

2-iminobutanoate

2-iminosuccinate

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

D-alanyl-D-alanine

DNA with lesion

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobalt-factor III

cobalt-sirohydrochlorin

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

protoheme

protoporphyrin IX

uroporphyrinogen-III

protoporphyrinogen IX

siroheme

oxygen

hydrogen sulfide

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

5,10-methenyltetrahydrofolate mono-L-glutamate

preQ₀

(indole-3-yl)acetonitrile

coenzyme A

(S)-NADHX

(R)-NADHX

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal