an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

β-nicotinate D-ribonucleotide

quinolinate

glycerone phosphate

α-ribazole

α-ribazole 5'-phosphate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

L-histidinol phosphate

histidinol

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

glycolate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

L-arginino-succinate

canavaninosuccinate

L-canavanine

prephenate

preuroporphyrinogen

(R)-4-phosphopantoate

(S)-mandelate

(R)-mandelate

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

phosphoenolpyruvate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

carbon monoxide

CO₂

selenophosphate

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

H₂O

oxaloacetate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

2-dehydropantoate

S-ribosyl-L-homocysteine

autoinducer 2

oxalate

(S)-2,3,4,5-tetrahydrodipicolinate

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

acetyl phosphate

(R)-mevalonate diphosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

(S)-dihydroorotate

deethylsimazine

N-ethylammeline

N⁵-carboxyaminoimidazole ribonucleotide

pimelate

pimeloyl-CoA

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

isopentenyl diphosphate

prenyl diphosphate

3-dehydroshikimate

histidinal

oxalosuccinate

(R)-5-phosphomevalonate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

3-phosphooxypyruvate

carboxyphosphate

imidazole acetol-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

N-(5-phosphoribosyl)-anthranilate

anthranilate

7-carboxy-7-deazaguanine

5-(methylsulfanyl)-ribulose 1-phosphate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

4'-phosphopantetheine

5-enolpyruvoyl-shikimate 3-phosphate

thiamine phosphate

thiamine diphosphate

D-erythro-imidazole-glycerol-phosphate

N-acetylglutamyl-phosphate

shikimate

shikimate 3-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

coenzyme B

CoB-CoM heterodisulfide

5-aminolevulinate

porphobilinogen

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

α-D-glucosamine 1-phosphate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

5-oxo-L-proline

orotidine 5'-phosphate

N-acetyl-L-glutamate 5-semialdehyde

carbonic acid

methanophenazine

dihydromethanophenazine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

hexulose 6-phosphate

ADP-D-glycero-β-D-manno-heptose

ADP-L-glycero-β-D-manno-heptose

(S)-4-amino-5-oxopentanoate

(R)-mevalonate

5-phospho-β-D-ribosylamine

α-D-ribose 1,5-bisphosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

7,8-didemethyl-8-hydroxy-5-deazariboflavin

carbamoyl phosphate

O-ureido-L-homoserine

H₂

coproporphyrinogen III

S-adenosyl 3-(methylsulfanyl)propylamine

(2S)-lactyl-2-diphospho-5'-guanosine

nicotinate adenine dinucleotide

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

L-homocysteine

ethylphosphate

N₂

adenosylcobalamin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cobalt-factor III

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-4

cobalt-precorrin-5A

adenosyl-cobinamide phosphate

cobalt-precorrin-5B

cobalt-precorrin-6B

cobalt-precorrin-6A

cobalt-precorrin-3

cobalt-sirohydrochlorin

cobalt-precorrin-2

Mg-protoporphyrin

uroporphyrinogen-III

uroporphyrinogen-I

protoporphyrinogen IX

protoporphyrin IX

oxygen

2-iminosuccinate

2-chloroacetate

3-phospho-D-glyceroyl-phosphate

(R)-glycerate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

(S)-4-hydroxymandelate

(R)-4-hydroxymandelate

(indole-3-yl)acetonitrile

preQ₀

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

ammonium

H⁺

Co²⁺

Mo²⁺

Ni²⁺

Mg²⁺

selenide

molybdate

nitrate

sulfate

selenate

hydrogencarbonate

sulfite

phosphate

diphosphate

triphosphate

chloride

agmatine

dehydrospermidine

putrescine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

glutathione

L-cysteate

3-sulfopyruvate

sulfoacetaldehyde

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

acetyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

3'-dephospho-CoA

succinyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

tributyrin

1,2-dibutyrin

methane

(indol-3-yl)acetate

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

pyridoxal 5'-phosphate

FMN

FAD

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

caldariellaquinone

caldariellaquinol

GMP

GTP

IMP

adenylo-succinate

GDP

ADP

AMP

ATP

dGDP

dIDP

dITP

IDP

ITP

dADP

dATP

dGTP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

XMP

hypoxanthine

adenosine

2'-deoxyuridine

2'-deoxycytidine

thymidine

dCTP

dUTP

dTTP

CTP

UTP

dUMP

dTMP

dCMP

CMP

UMP

dUDP

dTDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

uracil

thymine

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galactose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

coenzyme A

methyl-CoM

molybdopterin

oxidized coenzyme F₄₂₀-0

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

adenylyl molybdenum cofactor

bis(molybdenum cofactor)

bis(guanylyl molybdopterin) cofactor

precorrin-7

precorrin-6B

precorrin-6A

precorrin-5

precorrin-4

precorrin-3B

precorrin-3A

precorrin-1

precorrin-8x

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

molybdopterin adenine dinucleotide

7,8-dihydroneopterin

7,8-dihydromonapterin

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

orotate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

diacetyl

glycolaldehyde

acetaldehyde

formaldehyde

(S)-lactaldehyde

D-glyceraldehyde

α-D-ribofuranose

ethanol

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 2-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

N-acetyl-α-D-glucosamine 1-phosphate

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructofuranose 1-phosphate

daunorubicin

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

5-amino-4-imidazolecarboxyamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

chorismate

succinate

fumarate

L-aspartate

(S)-malate

cis-homoaconitate

(2R)-homocitrate

D-threo-isocitrate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

pyruvate

2-oxoglutarate

2-oxobutanoate

acetate

formate

(S)-lactate

butanoate

(R)-pantoate

L-α-amino-ε-keto-pimelate

carbamate

L-serine

L-glutamine

glycine

L-cysteine

L-tyrosine

L-threonine

L-arginine

L-histidine

L-lysine

L-glutamate

L-tryptophan

L-phenylalanine

L-methionine

L-alanine

L-isoleucine

L-leucine

L-valine

β-alanine

L-ornithine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-glutamate

L-citrulline

S-adenosyl-L-methionine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

L-canaline

S-adenosyl-L-homocysteine

meso-diaminopimelate