an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1-piperideine 6-carboxylate

1,2-dihydro-β-NADP

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

creatinine

S-ribosyl-L-homocysteine

autoinducer 2

dialurate

2-amino-3-carboxymuconate-6-semialdehyde

(R)-4'-phosphopantothenate

N-acetyl-D-muramate 6-phosphate

urea

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

2-maleylacetate

(R)-pantothenate

1,6-anhydro-N-acetyl-β-muramate

N-Formyl-L-kynurenine

acetoacetate

O-ureido-L-homoserine

nicotinate adenine dinucleotide

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

L-β-lysine

5-enolpyruvoyl-shikimate 3-phosphate

prephenate

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

thiamine diphosphate

acetyl phosphate

propanoyl phosphate

deethylsimazine

N-ethylammeline

3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine

3-phosphooxypyruvate

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(S)-2,3-dihydrodipicolinate

4-amino-4-deoxychorismate

glycolate

shikimate

shikimate 3-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

3-dehydroshikimate

xanthine

(S)-4-hydroxy-2-oxopentanoate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-oxo-L-proline

5,6-dimethylbenzimidazole

N-carbamoylputrescine

carbonic acid

(R)-1-amino-2-propanol O-2-phosphate

α-ribazole

α-ribazole 5'-phosphate

hydrogenobyrinate a,c-diamide

(E)-3-(methoxycarbonyl)pent-2-enedioate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

(R)-2,3-dihydroxy-3-methylpentanoate

4'-phosphopantetheine

prenyl diphosphate

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

3-ureidopropanoate

hydrogen peroxide

histidinal

histidinol

orotidine 5'-phosphate

(S)-dihydroorotate

selenophosphate

H₂

5'-phosphoguanylyl(3'→5')guanosine

carboxynorspermidine

norspermidine

(S)-2-amino-6-oxohexanoate

O-acetyl-L-serine

(R)-1-aminopropan-2-ol

7-carboxy-7-deazaguanine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

coproporphyrinogen III

DNA without lesion

hydroxypyruvate

1,4-dihydroxy-2-naphthoate

porphobilinogen

preuroporphyrinogen

β-nicotinate D-ribonucleotide

quinolinate

S-adenosyl 3-(methylsulfanyl)propylamine

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

canavaninosuccinate

L-canavanine

L-arginino-succinate

carboxyphosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

N-(5-phosphoribosyl)-anthranilate

anthranilate

5-amino-6-(D-ribitylamino)uracil

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

γ-L-glutamyl 5-phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

2-succinylbenzoate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

1,4-dihydroxy-2-naphthoyl-CoA

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

isochorismate

oxalosuccinate

CO₂

N-methylhydantoin

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

carbamoyl phosphate

α-D-glucosamine 1-phosphate

oxaloacetate

citrate

glycerone phosphate

3-methyl-2-oxobutanoate

2-dehydropantoate

phosphoenolpyruvate

H₂O

hydrogenobyrinate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

2-chloroacetate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

ubiquinol-8

menaquinol-7

menaquinol-8

demethylmenaquinol-7

demethylmenaquinol-8

3-demethylubiquinol-8

NADPH

NADH

NADP⁺

NAD⁺

(2E,6E)-farnesyl diphosphate

pristanate

selenide

hydrogencarbonate

phosphate

triphosphate

diphosphate

chloride

H⁺

ammonium

Fe²⁺

Mg²⁺

methanethiol

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

coenzyme M

L-cysteate

3-sulfopyruvate

(2Z)-2-aminobut-2-enoate

2-iminopropanoate

2-aminoprop-2-enoate

agmatine

cadaverine

putrescine

spermidine

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

D-alanyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

menadiol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

4-aminobenzoate

preQ₀

methyl-CoM

coenzyme A

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

7,8-dihydrofolate monoglutamate

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

MoO₂-molybdopterin cofactor

thio-molybdenum cofactor

thiamine

nicotinate

riboflavin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

menadione

phenylacetate

cis-dienelactone

trans-dienelactone

3'-dephospho-CoA

phenylacetyl-CoA

CoA-disulfide

succinyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

isobutanoyl-CoA

malonyl-CoA

acetyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

18-hydroxylinoleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

(Z)-15-tetracosenoyl-CoA

butanoyl-CoA

propanoyl-CoA

decanoyl-CoA

octanoyl-CoA

lauroyl-CoA

pristanoyl-CoA

cis-vaccenoyl-CoA

myristoyl-CoA

palmitoleoyl-CoA

stearoyl-CoA

palmitoyl-CoA

acetoacetyl-CoA

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

(3E)-2-oxohex-3-enedioate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

α,ω-9Z-octadecenedioate

3-(carbamoylamino)-2-methylpropanoate

trans-aconitate

cis-aconitate

D-threo-isocitrate

pyruvate

acetate

formate

(R)-lactate

butanoate

decanoate

octanoate

laurate

7-hydroxylaurate

(R)-glycerate

18-hydroxyoleate

18-hydroxystearate

16-hydroxypalmitate

(15Z)-tetracosenoate

α-linolenate

linoleate

stearate

palmitate

oleate

phytenate

1-palmitoyl-2-cis-vaccenoyl phosphatidate

1,2-dicis-vaccenoyl-phosphatidate

1-cis-vaccenoyl-2-palmitoleoyl-sn-glycerol-3-phosphate

1-myristoyl-2-palmitoleoyl-sn-glycerol 3-phosphate

1-palmitoyl-2-palmitoleoyl-sn-glycerol 3-phosphate

(R)-pantoate

orotate

(S)-1-pyrroline-5-carboxylate

4-deoxy-L-threo-hex-4-enopyranuronate

L-kynurenine

carbamate

L-serine

N-carbamoylsarcosine

(R)-β-lysine

β-glutamate

β-alanine

(R)-3-amino-2-methylpropanoate

L-proline

L-alanine

L-leucine

L-glutamine

glycine

D-glutamate

L-glutamate

L-lysine

L-histidine

L-arginine

L-tyrosine

L-tryptophan

L-phenylalanine

D-aspartate

D-alanine

L-saccharopine

L-aspartyl-4-phosphate

L-threonine 3-O-phosphate

3-phospho-L-serine

sarcosine

N-carbamoyl-L-aspartate

N-carbamoylglycine

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-acetyl-L-methionine

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-cysteine

L-cystathionine

L-threonine

L,L-diaminopimelate

L-asparagine

L-ornithine

L-isoleucine

L-valine

L-methionine

L-citrulline

L-canaline

O-phospho-L-homoserine

L-homoserine

O-succinyl-L-homoserine

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homocysteine

meso-diaminopimelate

3-phenyl-2-oxopropanoate

glyoxylate

2-oxobutanoate

2-oxoglutarate

sn-glycero-3-phosphoethanolamine

glycerol

ethanol

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

geranyl diphosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

1-(18-hydroxyoleoyl)-sn-glycrol 3-phosphate

1-oleoyl-sn-glycerol 3-phosphate

1-myristoyl-sn-glycerol 3-phosphate

1-palmitoyl-sn-glycerol 3-phosphate

1-cis-vaccenoyl-sn-glycerol-3-phosphate

1-[18-hydroxyoeoyl]-2-[18-hydroxy-lioleoyl]-sn-glycerol 3-phosphate

1-palmitoyl-2-myristoyl phosphatidate

1,2-dimyristoyl-sn-glycerol 3-phosphate

dioleoyl phosphatidate

5-dehydro-4-deoxy-D-glucuronate

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-β-D-glucosamine

D-glyceraldehyde

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

a peptidoglycan dimer (E. faecium, tetrapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

a peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing)

a peptidoglycan dimer with pentapeptide stem (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

diacetyl

formaldehyde

acetaldehyde

precorrin-6B

precorrin-7

precorrin-1

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-2

precorrin-3A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-8x

cobyrinate

adenosylcobalamin

cob(I)alamin

hydantoin

dipicolinate

dTMP

dCMP

5,6-dihydrouracil

5,6-dihydrothymine

UTP

dCTP

CTP

dTDP

dTTP

dUTP

dUMP

uracil

dUDP

UDP

dCDP

CDP

CMP

UMP

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

thymidine

thymine

adenine

guanine

hypoxanthine

preQ₁

xanthosine

guanosine

inosine

adenosine

2'-deoxyinosine

2'-deoxyadenosine

2'-deoxyguanosine

ITP

ATP

GTP

IDP

ADP

GDP

XMP

GMP

AMP

IMP

dITP

dGTP

dATP

dIDP

dADP

dGDP

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropteroate

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

ppGpp

cyclic-AMP

pppGpp

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

adenylo-succinate

(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA)

two adjacent thymidines in DNA

cyclic di-3',5'-guanylate

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

DNA with lesion

ethylphosphate

Mg-protoporphyrin

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

adenosyl-cobinamide phosphate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

adenosylcobinamide

adenosylcobyrate

protoheme

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

protoporphyrinogen IX

uroporphyrinogen-III

oxygen

hydrogen sulfide

2-iminobutanoate

2-iminosuccinate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate