an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

hydrogenobyrinate a,c-diamide

(S)-2-amino-6-oxohexanoate

ethanolamine

thiamine diphosphate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

prephenate

O-ureido-L-homoserine

L-arginino-succinate

canavaninosuccinate

carboxyphosphate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

N-acetylglutamyl-phosphate

D-erythro-imidazole-glycerol-phosphate

histidinal

histidinol

(R)-4'-phosphopantothenoyl-L-cysteine

thiamine phosphate

3-dehydroquinate

3-dehydroshikimate

5-(methylsulfanyl)-ribulose 1-phosphate

β-D-ribosylnicotinate

N-acetyl-D-galactosamine 6-phosphate

D-galactosamine-6-phosphate

L-canavanine

2-phosphoglycolate

coenzyme F₃₉₀-A

4-imidazolone-5-propanoate

glycolate

(R)-1-aminopropan-2-ol

α-ribazole

α-ribazole 5'-phosphate

xanthine

urea

urea-1-carboxylate

7-carboxy-7-deazaguanine

2-dehydropantoate

3-phosphooxypyruvate

nicotinate adenine dinucleotide

coproporphyrinogen III

(lipoyl)adenylate

4'-phosphopantetheine

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

deethylsimazine

N-ethylammeline

(R)-pantothenate

(R)-4'-phosphopantothenate

isopentenyl diphosphate

4-prenylphlorisobutyrophenone

prenyl diphosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

hydrogen peroxide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

carbon monoxide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-6-(D-ribitylamino)uracil

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

(R)-mevalonate

(R)-5-phosphomevalonate

aminoacetone

N-acetyl-L-glutamate 5-semialdehyde

imidazole acetol-phosphate

L-histidinol phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

β-nicotinate D-ribonucleotide

S-adenosyl 3-(methylsulfanyl)propylamine

3-methyl-2-oxobutanoate

glycerone phosphate

3-oxopropanoate

4-aminobutanoate

succinate semialdehyde

oxaloacetate

phosphoenolpyruvate

carbamoyl phosphate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

CO₂

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

formate

1-deoxy-L-glycero-tetrulose 4-phosphate

H₂O

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1-piperideine 6-carboxylate

(R)-4-phosphopantoate

S-ribosyl-L-homocysteine

autoinducer 2

(R)-mevalonate diphosphate

5,6-dimethylbenzimidazole

(R)-1-amino-2-propanol O-2-phosphate

hydrogenobyrinate

L-homocysteine

ethylphosphate

cob(II)yrinate a,c-diamide

adenosylcobinamide

adenosylcobyrate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cob(I)alamin

adenosylcobalamin

Mg-protoporphyrin

cob(I)inamide

adenosyl-cobinamide phosphate

uroporphyrinogen-III

protoporphyrinogen IX

protoporphyrin IX

oxygen

2-chloroacetate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-O-(α-D-mannosyl)-D-glycerate

2-O-(α-D-mannosyl)-3-phospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

ω-saturated C55 dolichol phosphate

preQ₀

ammonium

H⁺

Co²⁺

Mg²⁺

Mo²⁺

selenate

hydrogencarbonate

sulfate

molybdate

phosphate

triphosphate

diphosphate

chloride

(2E,6E)-farnesyl diphosphate

pristanate

glycerophosphoglycerol

glycerophosphoserine

sn-glycero-3-phosphoethanolamine

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

5-(2-hydroxyethyl)-4-methylthiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

L-cysteate

3-sulfopyruvate

CoA-disulfide

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(2S)-ethylmalonyl-CoA

(2R)-ethylmalonyl-CoA

3'-dephospho-CoA

α-linolenoyl-CoA

linoleoyl-CoA

malonyl-CoA

succinyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

isobutanoyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

lauroyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

nicotinamide

riboflavin

nicotinate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

FMNH₂

FMN

FAD

(R)-NADHX

(S)-NADHX

NADPH

NADH

NAD⁺

NADP⁺

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

cyclic-AMP

hypoxanthine

dGDP

dIDP

dITP

IDP

ITP

dADP

IMP

adenylo-succinate

GDP

ADP

5'-deoxyadenosine

XMP

GMP

AMP

dGTP

GTP

dATP

ATP

xanthosine

guanosine

inosine

adenosine

uridine

cytidine

2'-deoxyuridine

thymidine

2'-deoxycytidine

cyclic di-3',5'-guanylate

dTTP

dCTP

dUTP

CTP

UTP

dTMP

dUMP

dCMP

CMP

UMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

thymine

uracil

guanine

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactose

molybdopterin

(R)-lipoate

coenzyme A

oxidized coenzyme F₄₂₀-2

MoO₂-molybdopterin cofactor

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

precorrin-7

precorrin-8x

precorrin-6B

precorrin-6A

precorrin-5

precorrin-4

precorrin-3B

precorrin-3A

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

molybdopterin adenine dinucleotide

7,8-dihydroneopterin 3'-triphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

cyclic pyranopterin phosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

6-carboxy-5,6,7,8-tetrahydropterin

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

acetaldehyde

(S)-lactaldehyde

D-glyceraldehyde

ethanol

glycerol

1D-myo-inositol 3-monophosphate

1-(β-D ribofuranosyl)nicotinamide

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

keto-D-fructose

β-D-fructofuranose

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

saturated archaetidylserine

saturated archaetidylethanolamine

unsaturated archaetidylserine

unsaturated archaetidylethanolamine

geranyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-octaprenyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

3-decaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

3-nonaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinyl)- 6-(hydroxymethyl)-diketopiperazine

5-amino-4-imidazolecarboxyamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

chorismate

maleate

succinate

L-aspartate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

(2R)-homocitrate

cis-homoaconitate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

glyoxylate

4-(methylsulfanyl)-2-oxobutanoate

pyruvate

2-oxoglutarate

propanoate

octanoate

7-hydroxylaurate

laurate

decanoate

(15Z)-tetracosenoate

leukotriene-D4

leukotriene-E4

oleate

α-linolenate

linoleate

stearate

palmitate

phytenate

(R)-pantoate

acetate

carbamate

L-serine

glycine

L-asparagine

L-threonine

L-tyrosine

L-glutamine

L-cysteine

L-arginine

L-histidine

L-glutamate

L-proline

L-phenylalanine

L-alanine

L-leucine

L-tryptophan

L-methionine

β-alanine

D-aspartate

D-proline

L-cystathionine

L-aspartyl-4-phosphate

L-ornithine

N-formimino-L-glutamate

N-acetyl-L-citrulline

N-acetyl-L-ornithine

L-saccharopine

D-nopaline

L-2-amino-3-oxobutanoate

3-phospho-L-serine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

L-citrulline

L-canaline

L-homoserine

O-succinyl-L-homoserine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-glutamate-5-semialdehyde