an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

pyruvic oxime

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

H₂

CO₂

H₂O

pseudouridine 5'-phosphate

carbamoyl phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

phosphoenolpyruvate

3-phosphooxypyruvate

urea

S-methyl-5'-thioadenosine

S-adenosyl 3-(methylsulfanyl)propylamine

pimeloyl-CoA

pimelate

8-amino-7-oxononanoate

dethiobiotin

7,8-diaminopelargonate

prephenate

oxaloacetate

orotidine 5'-phosphate

N-succinyl-L,L-2,6-diaminopimelate

3-dehydroshikimate

3-dehydroquinate

chloramphenicol

nicotinate adenine dinucleotide

isopentenyl diphosphate

(R)-5-phosphomevalonate

(R)-mevalonate

5-enolpyruvoyl-shikimate 3-phosphate

carbonic acid

3-methyl-2-oxobutanoate

porphobilinogen

5-aminolevulinate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

L-histidinol phosphate

imidazole acetol-phosphate

shikimate 3-phosphate

glycerone phosphate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropylmalate

5-phospho-β-D-ribosylamine

thiamine phosphate

thiamine diphosphate

4'-phosphopantetheine

(S)-dihydroorotate

anthranilate

N-(5-phosphoribosyl)-anthranilate

carbon monoxide

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

histidinol

histidinal

CDP-glycerol

shikimate

selenophosphate

quinolinate

β-nicotinate D-ribonucleotide

preuroporphyrinogen

hydroxypyruvate

L-β-lysine

5-hydroxyindole acetaldehyde

5-hydroxytryptophol

3-methoxy-4-hydroxyphenylglycolaldehyde

indole-3-glycol aldehyde

indole-3-glycol

isobutanol

3-methylbutanal

3-methylbutanol

2-methylbutanal

2-methylbutanol

2-phenylethanol

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

2-dehydropantoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

D-erythro-imidazole-glycerol-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

hydrogenobyrinate a,c-diamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-3-methyl-2-oxopentanoate

dihydroxyacetone

(S)-4-amino-5-oxopentanoate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-deoxy-α-ribose 1-phosphate

5-amino-6-(D-ribitylamino)uracil

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

arsenite

(4Z)-2-oxohept-4-enedioate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

4-aminobutanoate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

L-arginino-succinate

canavaninosuccinate

O-ureido-L-homoserine

prenyl diphosphate

L-canavanine

3-deoxy-D-arabino-heptulosonate 7-phosphate

creatinine

dihydromethanophenazine

CoB-CoM heterodisulfide

methanophenazine

coenzyme B

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

4-amino-4-deoxychorismate

γ-L-glutamyl 5-phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

coproporphyrinogen III

citrate

hydrogenobyrinate

4-acetamidobutanoate

4-acetamidobutanal

N²-succinylglutamate

N²-succinyl-L-glutamate 5-semialdehyde

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

hexulose 6-phosphate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

α-ribazole 5'-phosphate

α-ribazole

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

oxalate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

DNA without lesion

hydroxylamine

coenzyme F₃₉₀-A

(2S)-lactyl-2-diphospho-5'-guanosine

1-deoxy-L-glycero-tetrulose 4-phosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

(R)-1-amino-2-propanol O-2-phosphate

5,6-dimethylbenzimidazole

dialurate

2-(sulfomethyl)thiazolidine-4-carboxylate

sulfoethylcysteine

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

(S)-2,3,4,5-tetrahydrodipicolinate

ammonia

citraconate

(2R,3S)-3-methylmalate

N⁵-carboxyaminoimidazole ribonucleotide

oxalosuccinate

2-(α-hydroxyethyl)thiamine diphosphate

(R)-mevalonate diphosphate

autoinducer 2

S-ribosyl-L-homocysteine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

4-amino-2-methyl-5-pyrimidinemethanol

crotonate

cyclohex-1,5-diene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

3-hydroxypimeloyl-CoA

3-oxopimeloyl-CoA

cyclohexane-1-carboxylate

cyclohexane-1-carbonyl-CoA

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

α-D-glucosamine 1-phosphate

(4-hydroxyphenyl)acetate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

(2E,6E)-farnesyl diphosphate

N-acetyl-L-glutaminyl-L-glutamine amide

N-acetyl-L-glutaminyl-L-glutamine

2-iminosuccinate

L-α-amino-ε-keto-pimelate

L-tryptophan

L-alanine

L-phenylalanine

L-isoleucine

L-leucine

L-valine

glycine

L-methionine

L-cysteine

L-glutamate

L-glutamine

L-aspartate

L-histidine

L-arginine

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-lysine

L-serine

L-asparagine

L-ornithine

L-threonine

L-tyrosine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

L-aspartate 4-semialdehyde

L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-homocysteine

O-phospho-L-homoserine

meso-diaminopimelate

L-selenomethionine

seleno-L-homocysteine

N-acetyl-L-glutamate

N-acetyl-L-methionine

3-phospho-L-serine

D-alanine

D-aspartate

creatine

ATP

ADP

AMP

GDP

GTP

dADP

dATP

dGDP

dGTP

GMP

XMP

adenylo-succinate

IMP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

ITP

IDP

dITP

dIDP

1-(5-phospho-β-D-ribosyl)-AMP

cyclic-AMP

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

ADP-D-ribose

ADP ribose 1''-phosphate

ADP ribose 1'',2''-cyclic phosphate

GDP-α-D-mannose

GDP-α-D-mannuronate

dTDP-α-D-glucose

UDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-glucosamine

adenine

uracil

thymine

dUMP

dTMP

dCMP

dTDP

dCDP

dUDP

dUTP

dCTP

dTTP

CDP

UDP

β-nicotinamide D-ribonucleotide

UTP

CTP

CMP

UMP

NAD⁺

NADP⁺

NADH

NADPH

thymidine

2'-deoxyuridine

2'-deoxycytidine

adenosine

uridine

cytidine

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

L-fuculose 1-phosphate

α-D-mannose 1-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

β-D-fructofuranose

keto-D-fructose

glycolaldehyde

α-D-ribofuranose

β-D-glucopyranose

α-D-glucopyranose

D-glyceraldehyde

glycerol

maltotriose

sucrose

maltohexaose

maltotetraose

maltopentaose

maltoheptaose

salicylaldehyde

phytyl diphosphate

(3S)-linalool

(3R)-linalool

geranyl diphosphate

apo-4'-lycopenal

apo-4'-lycopenoate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

3-octaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenol

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

3,4-dihydroxyphenylglycolaldehyde

3,4-dihydroxyphenylglycol

ethanol

propan-1-ol

phytol

butan-1-ol

(4-hydroxyphenyl)acetaldehyde

phenylacetaldehyde

benzaldehyde

phytenal

(S)-lactaldehyde

acetaldehyde

1-propanal

isobutanal

1-octanal

formaldehyde

butan-1-al

(R)-acetoin

caldariellaquinone

diacetyl

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

pyruvate

2-oxoglutarate

2-oxobutanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

salicylate

4-aminobenzoate

benzoate

acetate

orotate

(R)-pantoate

octanoate

phytenate

formate

propanoate

(S)-lactate

(R)-2-hydroxybutanoate

(R)-glycerate

(S)-2-hydroxyglutarate

cis-aconitate

D-threo-isocitrate

chorismate

(3E)-2-oxohex-3-enedioate

fumarate

succinate

(S)-malate

4-tyrosol

4-hydroxybenzoate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

4-methylphenol

caldariellaquinol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

3-methoxy-4-hydroxyphenylglycol

hydrogen cyanide

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

cyclic pyranopterin phosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

molybdopterin

7,8-dihydroneopterin 2',3'-cyclic phosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin 2'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

molybdopterin adenine dinucleotide

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

7,8-dihydropteroate

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5-methyltetrahydropteroyl tri-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

7,8-dihydromethanopterin

demethylated 7,8-dihydromethanopterin

7,8-dihydrofolate monoglutamate

riboflavin

FMN

FAD

FMNH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

adenosylcobalamin

sirohydrochlorin

cobyrinate

precorrin-5

precorrin-4

precorrin-6B

precorrin-8x

precorrin-7

precorrin-2

precorrin-1

precorrin-3B

precorrin-6A

precorrin-3A

cobalt-precorrin-2

cobalt-precorrin-5B

cobalt-precorrin-5A

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-precorrin-3

thiamine

nicotinate

pyridoxal 5'-phosphate

coenzyme A

methyl-CoM

coenzyme M

oxidized coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

(R)-NADHX

(S)-NADHX

glycine betaine

succinyl-CoA

acetyl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

3'-dephospho-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

2-methylbutanoyl-CoA

(E)-glutaconyl-CoA

glutaryl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

propanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

crotonyl-CoA

methane

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

agmatine

putrescine

spermidine

dehydrospermidine

sulfate

sulfite

selenide

thiosulfate

nitrate

hydrogensulfite

hydrogencarbonate

molybdate

phosphate

diphosphate

triphosphate

Fe³⁺

Mo²⁺

Fe²⁺

Co²⁺

ammonium

H⁺

3-(methylsulfanyl)propanal

methionol

(2R)-phospho-3-sulfolactate

sulfoacetaldehyde

3-sulfopyruvate

L-cysteate

(2R)-3-sulfolactate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

thiocyanate

chloramphenicol 3-acetate

2-octaprenylphenol

(R)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

oxygen

uroporphyrinogen-III

protoporphyrinogen IX

coproporphyrinogen I

uroporphyrinogen-I

siroheme

N₂

cob(II)yrinate a,c-diamide

cobalt-sirohydrochlorin

cob(II)yrinate c-monoamide

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

cobalt-factor III

cob(I)yrinate a,c-diamide

adenosyl-cobinamide phosphate

DNA with lesion