an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

5-hydroxyindole thiazolidine carboxylate

pyruvic oxime

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

(R)-mevalonate diphosphate

α-D-glucosamine 1-phosphate

2-(α-hydroxyethyl)thiamine diphosphate

H₂

5,6-dimethylbenzimidazole

dialurate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

1-deoxy-L-glycero-tetrulose 4-phosphate

carbon monoxide

acrylamide

acrylate

4-guanidinobutyramide

4-guanidinobutanoate

(indol-3-yl)acetamide

propionamide

N-succinyl-L,L-2,6-diaminopimelate

DNA without lesion

ammonia

hydroxylamine

pimeloyl-CoA

1,4-dihydroxy-2-naphthoate

γ-L-glutamyl 5-phosphate

2-oxopent-4-enoate

(S)-4-hydroxy-2-oxopentanoate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4S)-4-hydroxy-2-oxoheptanedioate

L-β-lysine

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

β-D-fructose 2,6-bisphosphate

4-amino-4-deoxychorismate

hydrogen selenide

O-acetyl-L-serine

N¹-(5-phospho-β-D-ribosyl)glycinamide

CDP-glycerol

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

3-dehydroshikimate

shikimate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-pyrimidinemethanol

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

hydrogen peroxide

2,3-didehydroadipyl-CoA

(E)-4-coumaroyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

oxalosuccinate

pseudouridine 5'-phosphate

(S)-dihydroorotate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

xanthine

hydroxypyruvate

O-ureido-L-homoserine

β-nicotinate D-ribonucleotide

quinolinate

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

dethiobiotin

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

thiamine phosphate

thiamine diphosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N-(5-phosphoribosyl)-anthranilate

anthranilate

P¹,P⁴-bis(5'-guanosyl) tetraphosphate

2-deoxygluconate

3-dehydro-2-deoxy-D-gluconate

nicotinate adenine dinucleotide

preuroporphyrinogen

(S)-4-amino-5-oxopentanoate

nicotine-glucuronide

cotinine

cotinine-glucuronide

N-acetyl-serotonin glucuronide

5-hydroxytryptophol glucuronide

L-thyroxine acyl β-D-glucuronide

L-thyroxine phenolic β-D-glucuronide

urea

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

5-aminolevulinate

porphobilinogen

carbamoyl phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

4'-phosphopantetheine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

2-dehydropantoate

glycerone phosphate

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

4-phosphooxy-L-threonine

3-phosphooxypyruvate

phosphoenolpyruvate

(R)-5-phosphomevalonate

prenyl diphosphate

isopentenyl diphosphate

orotidine 5'-phosphate

canavaninosuccinate

L-canavanine

L-arginino-succinate

3-methyl-2-oxobutanoate

4-methyl-2-oxopentanoate

(S)-3-methyl-2-oxopentanoate

citrate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(D-ribitylamino)uracil

5-methylcytosine

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

3'-phosphoadenylyl-sulfate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

5-phospho-β-D-ribosylamine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

oxaloacetate

(R)-1-amino-2-propanol O-2-phosphate

(R)-1-aminopropan-2-ol

α-ribazole

α-ribazole 5'-phosphate

2-C-methyl-D-erythritol 4-phosphate

prephenate

enol-phenylpyruvate

CO₂

2-phenylethanol

2-methylbutanol

2-methylbutanal

3-methylbutanol

3-methylbutanal

isobutanol

indole-3-glycol

indole-3-glycol aldehyde

3-methoxy-4-hydroxyphenylglycolaldehyde

5-hydroxytryptophol

5-hydroxyindole acetaldehyde

(R)-mevalonate

histidinal

histidinol

L-histidinol phosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

H₂O

uroporphyrinogen-I

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

Mg-protoporphyrin

siroheme

hydrogen sulfide

oxygen

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2,3-diphospho-D-glycerate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate

S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine

(R)-methylmalonate-semialdehyde

(S)-methylmalonate-semialdehyde

5,10-methenyltetrahydrofolate mono-L-glutamate

(S)-3-hydroxy-isobutanoate

2-octaprenylphenol

superoxide

dimethyl sulfide

methionol

3-(methylsulfanyl)propanal

glutathione

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

coenzyme M

L-cysteate

3-sulfopyruvate

(R)-S-lactoylglutathione

3-sulfino-L-alanine

H⁺

ammonium

Fe²⁺

Mg²⁺

Co²⁺

trimethyl sulfonium

hydrogensulfite

sulfate

nitrate

nitrite

selenide

thiosulfate

hydrogencarbonate

sulfite

selenate

phosphate

triphosphate

diphosphate

(2Z)-2-aminobut-2-enoate

agmatine

dehydrospermidine

spermidine

putrescine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

N-acetyl-serotonin

triiodothyroacetate ether glucuronide

3,3',5-triiodothyroacetate

triiodothyroacetate ester glucuronide

tetraiodothyroacetate ester glucuronide

tetraiodothyroacetate

tetraiodothyroacetate ether glucuronide

3,5,3'-triiodo-L-thyronine acyl β-D-glucuronide

3,5,3'-triiodo-L-thyronine

3,5,3'-triiodo-L-thyronine phenolic β-D-glucuronide

L-thyroxine

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

allantoate

acetamide

(S)-(+)-allantoin

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

nicotinamide

methane

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

3-oxo-4-pregnene-20-carboxyl-CoA

3,22-dioxochol-4-en-24-oyl-CoA

(indol-3-yl)acetate

2-methylbutanoyl-CoA

2-methylacetoacetyl-CoA

4-hydroxybutanoyl-CoA

3-hydroxyisovaleryl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

methylacrylyl-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

succinyl-CoA

malonyl-CoA

(5E)-3-oxo-dodec-5-enoyl-CoA

(3E)-dec-3-enoyl-CoA

5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA

(3Z,5E)-dodeca-3,5-dienoyl-CoA

4-trans-3-oxo-undecenoyl-CoA

2-trans-nonenoyl-CoA

6-trans-3-oxo-tridecenoyl-CoA

4-trans-undecenoyl-CoA

6-cis, 3-oxo-tridecenoyl-CoA

4-cis-undecenoyl-CoA

4-hydroxybenzoyl-CoA

(+)-7-epi-jasmonoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-butanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-hexanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

acetyl-CoA

3'-dephospho-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

crotonyl-CoA

(2E)-oct-2-enoyl-CoA

(2E)-dec-2-enoyl-CoA

(3Z)-dodec-3-enoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

cerotoyl-CoA

2-carboxy-cerotoyl-CoA

propanoyl-CoA

butanoyl-CoA

hexanoyl-CoA

decanoyl-CoA

lauroyl-CoA

octanoyl-CoA

3-oxoadipyl-CoA

acetoacetyl-CoA

3-oxooctanoyl-CoA

3-oxododecanoyl-CoA

3-oxodecanoyl-CoA

3-oxohexanoyl-CoA

3-oxo-(5Z)-tetradecenoyl-CoA

3-oxo-myristoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

D-glucono-1,5-lactone

mycophenolic acid phenolic glucuronide

mycophenolic acid O-acyl-glucuronide

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

demethylmenaquinol-8

methyl-CoM

coenzyme A

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

N¹⁰-formyldihydrofolate

nicotinate

riboflavin

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-1

precorrin-5

precorrin-3A

precorrin-7

precorrin-8x

precorrin-6B

precorrin-3B

precorrin-4

precorrin-2

cobalt-precorrin-2

cobyrinate

sirohydrochlorin

cob(I)alamin

adenosylcobalamin

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 3'-triphosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

guanine

adenine

2'-deoxyinosine

2'-deoxyguanosine

2'-deoxyadenosine

xanthosine

guanosine

inosine

adenosine

hypoxanthine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

GMP

AMP

IMP

XMP

ITP

GTP

ATP

dTMP

dTDP

dTTP

dCMP

dUMP

orotate

cytosine

uracil

dUDP

UDP

dCDP

CDP

dUTP

UTP

dCTP

CTP

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

5-fluorouracil

cytidine

uridine

thymine

CMP

UMP

hydrogen cyanide

4-tyrosol

3-methoxy-4-hydroxyphenylglycol

phenylacetaldehyde

(4-hydroxyphenyl)acetaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

3,4-dihydroxyphenylglycol

3,4-dihydroxyphenylglycolaldehyde

4-aminobenzoate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

cis-aconitate

D-threo-isocitrate

(R)-lactate

propanoate

pyruvate

acetate

formate

D-gluconate

mycophenolate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

2-oxoglutarate

L-serine

(R)-β-lysine

L-alanine

L-leucine

glycine

L-glutamine

L-glutamate

L-lysine

L-arginine

L-histidine

L-cysteine

L-tyrosine

L-asparagine

L-threonine

L-tryptophan

L-phenylalanine

L-aspartyl-4-phosphate

N-acetyl-L-citrulline

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

L-threonine 3-O-phosphate

3-phospho-L-serine

L-citrulline

L-valine

L-isoleucine

S-sulfo-L-cysteine

L-ornithine

L-homocysteine

L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

S-(4-hydroxy-nonenal-3-yl)-L-cysteine

L-selenocysteine

L-methionine

L,L-diaminopimelate

a coenzyme-A group

methylglyoxal

diacetyl

butan-1-al

isobutanal

1-propanal

acetaldehyde

phytenal

D-glyceraldehyde

β-D-glucopyranose

α-D-ribofuranose

butan-1-ol

methanol

propan-1-ol

ethanol

phytol

D-sorbitol

L-iditol

(3R)-linalool

(3S)-linalool

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

(2E,6E)-farnesyl diphosphate

oleanolate

oleanolate 3 β-D-glucuronoside

3-octaprenyl-4-hydroxybenzoate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

glucosyl-(heptosyl)₃-Kdo₂-lipid A-phosphate

glucosyl-(heptosyl)₃-glucosyluronate-Kdo₂-lipid A-phosphate

trans-3'-hydroxycotinine

trans-3-hydroxycotinine-glucuronide

(S)-nicotine

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

keto-L-sorbose

keto-D-fructose

β-D-fructofuranose

sucrose 6^F-phosphate

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

cyclic-AMP

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

5-fluorocytosine

P¹,P⁴-bis(5'-adenosyl) tetraphosphate

β-nicotinamide D-ribonucleotide

2-iminosuccinate

2-iminobutanoate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

γ-L-glutamyl-L-cysteine

DNA with lesion

cobalt-factor III

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobalt-sirohydrochlorin

cob(I)yrinate a,c-diamide

cob(I)inamide

adenosyl-cob(III)yrinate a,c-diamide

adenosyl-cobinamide phosphate

adenosylcobyrate

adenosylcobinamide

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate