an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

1,4-dihydroxy-2-naphthoate

N-succinyl-L,L-2,6-diaminopimelate

dialurate

(R)-1-amino-2-propanol O-2-phosphate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

hydroxypyruvate

(R)-4'-phosphopantothenate

lipid IV_A

lipid X

lipid A disaccharide (E. coli)

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

chloramphenicol

thiamine diphosphate

4-methyl-3-oxoadipate

2-dehydro-3-deoxy-D-gluconate

S-methyl-5'-thioadenosine

L-histidinol phosphate

2-deoxygluconate

3-dehydro-2-deoxy-D-gluconate

N-acetyl-β-D-mannosaminuronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol

(enterobacterial common antigen)-undecaprenyl diphosphate

3-deoxy-α-D-manno-2-octulosonate

(2R)-2-amino-4-oxopentanoate

3-dehydroquinate

L-selenocystathionine

formamide

2-dehydropantoate

anthranilate

N-(5-phosphoribosyl)-anthranilate

3-ureidopropanoate

prephenate

2-keto-D-gluconate

2,5-didehydro-D-gluconate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

(R)-pantothenate

urea-1-carboxylate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-2-amino-6-ketopimelate

O-acetyl-L-serine

glycolate

ammonia

enol-phenylpyruvate

1,2-dihydro-β-NADP

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

N²-succinylglutamate

citrate

5,6-dimethylbenzimidazole

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

α-D-ribose 1,5-bisphosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

histidinal

histidinol

urea

4-imidazolone-5-propanoate

urocanate

butanoyl phosphate

acetoacetate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

hydrogen peroxide

porphobilinogen

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

3-hydroxypropanal

propanoyl phosphate

dihydroxyacetone

α-ribazole 5'-phosphate

carboxyphosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

pimeloyl-CoA

8-amino-7-oxononanoate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

N⁵-carboxyaminoimidazole ribonucleotide

2-C-methyl-D-erythritol 4-phosphate

quinolinate

glycerone phosphate

nicotinate adenine dinucleotide

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

phosphoenolpyruvate

shikimate

5-amino-6-(D-ribitylamino)uracil

DNA without lesion

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

xanthine

3-dehydroshikimate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

α-ribazole

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

prenyl diphosphate

L-canavanine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

3-deoxy-D-manno-octulosonate 8-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

orotidine 5'-phosphate

carbamoyl phosphate

acetyl phosphate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

selenophosphate

S-adenosyl 3-(methylsulfanyl)propylamine

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-dihydroorotate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

coproporphyrinogen III

CO₂

oxaloacetate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

γ-L-glutamyl 5-phosphate

3-deoxy-D-glycero-2,5-hexodiulosonate

H₂O

DNA with lesion

L-homocysteine

ethylphosphate

carboxyphosphinopyruvate

3-(hydroxyphosphinoyl)pyruvate

1-carboxyvinyl carboxyphosphonate

hydrogen cyanide

adenosylcobalamin

cob(I)alamin

adenosyl-cobinamide phosphate

cobalt-precorrin-3

cobalt-precorrin-5A

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cob(I)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-precorrin-4

Mg-protoporphyrin

protoheme

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

uroporphyrinogen-I

coproporphyrinogen I

hydrogen sulfide

oxygen

2-iminobutanoate

2-iminopropanoate

2-iminosuccinate

2-chloroacetate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2R)-2,3-dihydroxy-3-methylbutanoate

N-acetyl-D-mannosamine 6-phosphate

N-acetyl-β-neuraminate 9-phosphate

CMP-N-acetyl-β-neuraminate

(indole-3-yl)acetonitrile

preQ₀

chloramphenicol 3-acetate

N-acetyl-β-neuraminate

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5-chloro-4-hydroxy-2-oxopentanoate

5-chloro-5-deoxy-D-ribonate

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

H⁺

ammonium

Mo²⁺

Fe²⁺

Co²⁺

Mg²⁺

thiosulfate

sulfite

hydrogensulfite

hydrogencarbonate

selenide

phosphate

triphosphate

diphosphate

chloride

(2E,6E)-farnesyl diphosphate

pristanate

glycine betaine

choline

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

spermidine

putrescine

glutathione

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

2-methylacetoacetyl-CoA

(R)-2-hydroxyglutaryl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(E)-glutaconyl-CoA

succinyl-CoA

isobutanoyl-CoA

malonyl-CoA

acetyl-CoA

3'-dephospho-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

butanoyl-CoA

propanoyl-CoA

lauroyl-CoA

octanoyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxoadipyl-CoA

4-methyl-3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

glycocholate

cholate

(indol-3-yl)acetate

nicotinate

riboflavin

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

menadione

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

menaquinol-8

menaquinol-6

menaquinol-7

menaquinol-12

menaquinol-13

menaquinol-11

menaquinol-10

menaquinol-9

demethylmenaquinol-8

demethylmenaquinol-10

demethylmenaquinol-6

demethylmenaquinol-7

demethylmenaquinol-12

demethylmenaquinol-13

demethylmenaquinol-11

demethylmenaquinol-9

cyclic-AMP

cyclic-GMP

5'-deoxyadenosine

pppGpp

ppGpp

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

dGTP

dGDP

dATP

dADP

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

adenylo-succinate

GDP

XMP

GMP

IMP

hypoxanthine

GTP

ADP

ATP

AMP

xanthosine

guanosine

inosine

adenosine

uridine

cytidine

2'-deoxycytidine

2'-deoxyuridine

thymidine

cyclic di-3',5'-guanylate

5-hydroxy-CTP

5-hydroxy-CMP

dTTP

dCTP

dUTP

UTP

CTP

dUMP

dTMP

dCMP

CMP

UMP

dUDP

dTDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-glucose

GDP-α-D-mannose

GDP-β-L-fucose

ADP-α-D-glucose

preQ₁

thymine

uracil

guanine

adenine

5,6-dihydrouracil

5,6-dihydrothymine

CMP-3-deoxy-β-D-manno-octulosonate

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-4-amino-4-deoxy-β-L-arabinopyranose

UDP-β-L-threo-pentapyranos-4-ulose

UDP-α-D-glucuronate

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-4-acetamido-4,6-dideoxy-α-D-galactose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

coenzyme A

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

precorrin-6B

precorrin-7

precorrin-8x

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

orotate

toluene

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2,3-dihydroxybenzoate

menadiol

diacetyl

acetone

6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone

3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone

methylglyoxal

acetaldehyde

1-propanal

butan-1-al

phytenal

L-glyceraldehyde

β-D-ribopyranose

β-D-galactopyranose

β-D-mannopyranose

aldehydo-D-mannose

propan-1-ol

butan-1-ol

ethanol

phytol

glycerol

D-mannitol

(S)-propane-1,2-diol

1-(β-D ribofuranosyl)nicotinamide

5-dehydro-4-deoxy-D-glucuronate

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

α,α-trehalose

keto-D-fructose

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-α-D-glucosamine 1-phosphate

D-xylulose

β-D-fructofuranose

4-deoxy-L-threo-hex-4-enopyranuronate

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (mycobacteria)

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (E. faecium, tetrapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing)

a peptidoglycan dimer with pentapeptide stem (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)₅-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

D-ribulose-1,5-bisphosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α,α-trehalose 6-phosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

geranyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-heptaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinyl)- 6-(hydroxymethyl)-diketopiperazine

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

chorismate

succinate

fumarate

L-aspartate

(S)-malate

α,ω-9Z-octadecenedioate

3-(carbamoylamino)-2-methylpropanoate

3-oxoadipate

3-phenyl-2-oxopropanoate

pyruvate

2-oxobutanoate

2-oxoglutarate

acetate

formate

propanoate

(R)-lactate

butanoate

decanoate

7-hydroxylaurate

laurate

octanoate

(15Z)-tetracosenoate

leukotriene-D4

leukotriene-E4

linoleate

α-linolenate

stearate

palmitate

oleate

phytenate

(R)-pantoate

L-α-amino-ε-keto-pimelate

carbamate

L-serine

L-cysteine

L-asparagine

L-glutamine

glycine

L-threonine

L-tyrosine

L-arginine

L-histidine

L-lysine

L-glutamate

L-methionine

L-proline

L-alanine

L-tryptophan

L-isoleucine

L-leucine

L-valine

L-phenylalanine

β-alanine

(R)-3-amino-2-methylpropanoate

D-glutamate

D-aspartate

D-alanine

L,L-diaminopimelate

L-cystathionine

L-isoglutamine

L-ornithine

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

formyl-L-isoglutamine

N-formimino-L-glutamate

N-acetyl-L-citrulline

N-acetyl-L-ornithine

seleno-L-homocysteine

(2S, 3S)-3-methylaspartate

N-carbamoylglycine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

L-citrulline

hypoglycin A

L-aspartate 4-semialdehyde

L-canaline

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homoserine

O-phospho-L-homoserine

L-glutamate-5-semialdehyde

meso-diaminopimelate

hypoglycin B

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-cysteinylglycine

D-alanyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine