an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

4-phosphooxy-L-threonine

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

2-dehydropantoate

L-histidinol phosphate

3-amino-1-hydroxyacetone 1-phosphate

(R)-pantothenate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

xanthine

S-Inosyl-L-homocysteine

porphobilinogen

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

4'-phosphopantetheine

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

orotidine 5'-phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

3-deoxy-α-D-manno-2-octulosonate

3-deoxy-D-manno-octulosonate 8-phosphate

5-oxo-L-proline

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

hydrogen peroxide

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

coenzyme B

CoB-CoM heterodisulfide

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

creatinine

(S)-mandelate

(R)-mandelate

selenophosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

DNA without lesion

methanophenazine

dihydromethanophenazine

dethiobiotin

carbon monoxide

coproporphyrinogen III

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

5-enolpyruvoyl-shikimate 3-phosphate

N-(5-phosphoribosyl)-anthranilate

3-ureidopropanoate

3-phosphooxypyruvate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N-acetyl-L-glutamate 5-semialdehyde

O-ureido-L-homoserine

quinolinate

adenosine 5'-phosphosulfate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

carbamoyl phosphate

carboxyphosphate

nicotinate adenine dinucleotide

oxalosuccinate

dihydroxyacetone

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

2-C-methyl-D-erythritol 4-phosphate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropylmalate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

3-methyl-2-oxobutanoate

CO₂

phosphoenolpyruvate

glycerone phosphate

anthranilate

oxaloacetate

citrate

H₂

γ-L-glutamyl 5-phosphate

N-acetylglutamyl-phosphate

L-arginino-succinate

canavaninosuccinate

L-canavanine

H₂O

ammonia

enol-phenylpyruvate

1,2-dihydro-β-NADP

lipid X

lipid A disaccharide (E. coli)

lipid IV_A

3-oxo-3-phenylpropanoyl-CoA

(S)-1-phenylethanol

2-amino-3-carboxymuconate-6-semialdehyde

preuroporphyrinogen

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

(R)-4'-phosphopantothenate

1,4-dihydroxy-2-naphthoyl-CoA

1,4-dihydroxy-2-naphthoate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

selenodiglutathione

glutathioselenol

hydrogen selenide

glutathione disulfide

3-dehydroshikimate

acetoacetate

urea

mercuriphenyl acetate

2-methyl-1,4-benzoquinone

methyl-1,4-benzoquinol

(S)-dihydroorotate

histidinal

histidinol

glycolate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

propanoyl phosphate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

shikimate

shikimate 3-phosphate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

adenosine 5'-phosphoselenate

7-carboxy-7-deazaguanine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

hydroxylamine

3'-phosphoadenylyl-sulfate

3-hydroxypropanoate

4-aminobutanoate

2-succinylbenzoate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

L-β-lysine

(R)-4'-phosphopantothenoyl-L-cysteine

DNA with lesion

L-homocysteine

phenylacetate

ethylphosphate

nitrous oxide

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

Mg-protoporphyrin

protoheme

protoporphyrinogen IX

uroporphyrinogen-I

protoporphyrin IX

uroporphyrinogen-III

siroheme

oxygen

Hg⁰

2-iminosuccinate

2-iminobutanoate

2-chloroacetate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-4-hydroxymandelate

(R)-4-hydroxymandelate

2-octaprenylphenol

preQ₀

(indole-3-yl)acetonitrile

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

Fe³⁺

H⁺

K⁺

ammonium

Co²⁺

Mo²⁺

Hg²⁺

Mg²⁺

Fe²⁺

sulfite

hydrogencarbonate

molybdate

sulfate

OH^-

selenite

selenate

selenide

nitrite

superoxide

phosphate

diphosphate

triphosphate

chloride

hydroxyl radical

pristanate

sn-glycero-3-phosphoethanolamine

(2Z)-2-aminobut-2-enoate

putrescine

spermidine

S-(hydroxymethyl)glutathione

glutathione

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

coenzyme M

L-cysteate

3-sulfopyruvate

(R)-2-hydroxyglutaryl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

(E)-glutaconyl-CoA

malonyl-CoA

phenylacetyl-CoA

benzoyl-CoA

4-hydroxybenzoyl-CoA

3'-dephospho-CoA

2-methylacetoacetyl-CoA

succinyl-CoA

isobutanoyl-CoA

acetyl-CoA

(2S)-ethylmalonyl-CoA

(2R)-ethylmalonyl-CoA

3-hydroxypropanoyl-CoA

4-hydroxybutanoyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

butanoyl-CoA

decanoyl-CoA

lauroyl-CoA

octanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

cholest-4-en-3-one

cholesterol

cholest-5-en-3-one

(indol-3-yl)acetate

riboflavin

nicotinate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

caldariellaquinone

caldariellaquinol

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

pppGpp

ppGpp

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

hypoxanthine

5'-deoxyadenosine

IDP

ITP

dIDP

dITP

adenylo-succinate

dATP

dADP

dGTP

dGDP

GTP

GDP

AMP

IMP

GMP

XMP

ADP

ATP

isoguanine

8-oxo-dGTP

8-oxo-GTP

cyclic-GMP

(R)-NADPHX

(S)-NADPHX

adenosine

inosine

guanosine

xanthosine

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

cyclic di-3',5'-guanylate

2-hydroxy-dATP

5-hydroxy-CTP

dTTP

dCTP

dUTP

UTP

CTP

dUMP

dTMP

dCMP

CMP

UMP

dTDP

dUDP

dCDP

UDP

CDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

GDP-α-D-mannuronate

ADP-α-D-glucose

uracil

thymine

guanine

adenine

5,6-dihydrouracil

5,6-dihydrothymine

CMP-3-deoxy-β-D-manno-octulosonate

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-3-dehydro-6-deoxy-α-D-galactopyranose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

CDP-3,6-dideoxy-D-glycero-4-hexulose

CDP-ascarylose

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

coenzyme A

(S)-1-pyrroline-5-carboxylate

precorrin-2

precorrin-1

sirohydrochlorin

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

orotate

acetophenone

3-oxo-3-phenylpropanoate

ethylbenzene

benzene

4-hydroxybenzoate

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2,3-dihydroxybenzoate

protocatechuate

diacetyl

methylglyoxal

butan-1-al

formaldehyde

acetaldehyde

D-glyceraldehyde

ethanol

butan-1-ol

glycerol

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

1-(β-D ribofuranosyl)nicotinamide

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

4-phospho-D-erythronate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

3-octaprenyl-4-hydroxybenzoate

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

chorismate

L-aspartate

succinate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

3-(carbamoylamino)-2-methylpropanoate

3-carboxy-cis,cis-muconate

cis-aconitate

D-threo-isocitrate

3-oxoadipate

3-phenyl-2-oxopropanoate

pyruvate

2-oxoglutarate

2-oxobutanoate

glyoxylate

acetate

formate

propanoate

(R)-lactate

butanoate

decanoate

7-hydroxylaurate

laurate

octanoate

4-hydroxybutanoate

(15Z)-tetracosenoate

linoleate

α-linolenate

stearate

palmitate

oleate

phytenate

(R)-pantoate

carbamate

L-serine

L-tyrosine

glycine

L-threonine

L-glutamine

L-cysteine

L-histidine

L-lysine

L-arginine

L-glutamate

L-proline

L-leucine

L-valine

L-alanine

L-phenylalanine

L-isoleucine

L-tryptophan

L-methionine

creatine

β-alanine

(R)-β-lysine

(R)-3-amino-2-methylpropanoate

D-alanine

L-ornithine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

sarcosine

N-carbamoylglycine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

L-citrulline

L-homoserine

L-canaline

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

meso-diaminopimelate

γ-L-glutamyl-L-cysteine