an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

CO₂

3-methyl-2-oxobutanoate

3-deoxy-D-arabino-heptulosonate 7-phosphate

phosphoenolpyruvate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

glycerone phosphate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

5-phospho-β-D-ribosylamine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N¹-(5-phospho-β-D-ribosyl)glycinamide

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

4'-phosphopantetheine

S-methyl-5-thio-α-D-ribose 1-phosphate

S-methyl-5'-thioadenosine

5-deoxy-α-ribose 1-phosphate

1-pyrroline

2-C-methyl-D-erythritol 4-phosphate

oxaloacetate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

S-adenosyl 3-(methylsulfanyl)propylamine

oxalosuccinate

γ-L-glutamyl 5-phosphate

dethiobiotin

α-D-glucosamine 1-phosphate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

succinate semialdehyde

4-aminobutanoate

3-oxopropanoate

1,4-dihydroxy-2-naphthoyl-CoA

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

(E)-4-coumaroyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

2,3-didehydroadipyl-CoA

carboxyphosphate

carbamoyl phosphate

anthranilate

7,8-diaminopelargonate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

8-amino-7-oxononanoate

citrate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

quinolinate

β-nicotinate D-ribonucleotide

3-dehydroshikimate

3-dehydroquinate

isopentenyl diphosphate

thiamine diphosphate

prephenate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

prenyl diphosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N⁵-carboxyaminoimidazole ribonucleotide

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

histidinol

histidinal

L-histidinol phosphate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

(R)-4'-phosphopantothenoyl-L-cysteine

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

5-oxo-L-proline

propanoyl phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

N-ethylammeline

deethylsimazine

nicotinate adenine dinucleotide

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(S)-2,3-dihydrodipicolinate

selenophosphate

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

3-ureidopropanoate

β-D-ribosylnicotinate

urocanate

4-imidazolone-5-propanoate

7-carboxy-7-deazaguanine

2-succinylbenzoate

dihydromethanophenazine

CoB-CoM heterodisulfide

methanophenazine

coenzyme B

L-canavanine

canavaninosuccinate

L-arginino-succinate

4-methyl-2-oxopentanoate

2-oxovalerate

3-ethylmalate

(2S)-2-isopropyl-3-oxosuccinate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

2-dehydro-3-deoxy-D-gluconate

coproporphyrinogen III

hydrogen peroxide

H₂

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

porphobilinogen

preuroporphyrinogen

xanthine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

4-prenylphlorisobutyrophenone

L-quinate

3-phosphooxypyruvate

glycolate

hop-22(29)-ene

squalene

carbonic acid

2-maleylacetate

4-methyl-3-oxoadipate

(E)-glutaconate

2-ketocyclohexane-1-carbonyl-CoA

2-hydroxy-cyclohexane-1-carbonyl-CoA

orotidine 5'-phosphate

N-(5-phosphoribosyl)-anthranilate

ManNAc-GlcNAc-PP-undecaprenol

N-acetyl-α-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol

urea

N-Formyl-L-kynurenine

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

2,5-didehydro-D-gluconate

2-keto-D-gluconate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

thiamine phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

ethanolamine

DNA without lesion

γ-glutamyl-L-putrescine

(S)-dihydroorotate

pimeloyl-CoA

O-ureido-L-homoserine

α-ribazole 5'-phosphate

5,6-dimethylbenzimidazole

4-amino-4-deoxychorismate

shikimate

2-dehydropantoate

(R)-pantothenate

O-acetyl-L-serine

carbon monoxide

3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine

hydrogen selenide

(R)-4'-phosphopantothenate

glutathione disulfide

4-(γ-L-glutamylamino)butanoate

4-(γ-L-glutamylamino)butanal

2-amino-3-carboxymuconate-6-semialdehyde

acetoacetate

(4-hydroxyphenyl)acetate

isochorismate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

1,4-dihydroxy-2-naphthoate

formamide

glutathioselenol

selenodiglutathione

4-oxoglutaramate

1,2-dihydro-β-NADP

enol-phenylpyruvate

ammonia

sulfate

molybdate

hydrogencarbonate

sulfite

selenate

superoxide

selenide

OH^-

selenite

chloride

phosphate

diphosphate

triphosphate

Fe³⁺

Mo²⁺

Co²⁺

Mg²⁺

Fe²⁺

ammonium

H⁺

5-chloro-4-hydroxy-2-oxopentanoate

5-chloro-5-deoxy-D-ribonate

2-chloroacetate

preQ₀

(indole-3-yl)acetonitrile

(R)-2-hydroxyglutarate

2-octaprenylphenol

(2R)-2,3-dihydroxy-3-methylbutanoate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-iminobutanoate

2-iminosuccinate

2-iminopropanoate

oxygen

hydrogen sulfide

Mg-protoporphyrin

protoporphyrin IX

coproporphyrinogen I

uroporphyrinogen-I

uroporphyrinogen-III

protoporphyrinogen IX

protoheme

cob(I)alamin

adenosylcobalamin

cobyrinate

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

adenosylcobinamide

cob(I)inamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-6A

cobalt-precorrin-5B

phenylacetate

L-homocysteine

4-methylphenol

DNA with lesion

D-alanyl-D-alanine

carbamate

L-kynurenine

L-aspartyl-4-phosphate

trans-4-hydroxy-L-proline

N-carbamoylglycine

formyl-L-isoglutamine

N-acetyl-L-ornithine

N-formimino-L-glutamate

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-cysteine

L-methionine

L-tryptophan

L-serine

L-glutamate

L-glutamine

L-alanine

L-ornithine

L-cystathionine

L-leucine

L-aspartate

L-arginine

L-isoleucine

L-phenylalanine

L-proline

L-lysine

L-histidine

L,L-diaminopimelate

L-valine

L-threonine

L-tyrosine

L-isoglutamine

D-glutamate

D-alanine

glycine

β-alanine

β-glutamate

(R)-3-amino-2-methylpropanoate

L-citrulline

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

O-succinyl-L-homoserine

S-adenosyl-L-methionine

L-homoserine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-canaline

meso-diaminopimelate

decanoate

laurate

7-hydroxylaurate

octanoate

acetate

pyruvate

formate

propanoate

butanoate

2-oxoglutarate

2-oxobutanoate

4-(methylsulfanyl)-2-oxobutanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

3-oxoadipate

cis-aconitate

(2R)-homocitrate

3-carboxy-cis,cis-muconate

cis-homoaconitate

D-threo-isocitrate

3-(carbamoylamino)-2-methylpropanoate

chorismate

(3E)-2-oxohex-3-enedioate

α,ω-9Z-octadecenedioate

fumarate

succinate

(S)-malate

protocatechuate

4-aminobenzoate

orotate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

4-deoxy-L-threo-hex-4-enopyranuronate

pristanate

(15Z)-tetracosenoate

palmitate

stearate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

phytenate

oleate

linoleate

α-linolenate

4-hydroxybutanoate

nicotinamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phlorisovalerophenone

4-prenylphlorisovalerophenone

deoxycohumulone

deoxyhumulone

(2E,6E)-farnesyl diphosphate

trans,octacis-decaprenyl phosphate

geranyl diphosphate

3-octaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

1-(β-D ribofuranosyl)nicotinamide

5-dehydro-4-deoxy-D-glucuronate

maltopentaose

maltohexaose

maltotetraose

maltoheptaose

maltotriose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-tagatofuranose 1,6-bisphosphate

D-fructose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

α-L-arabinopyranose

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

acetaldehyde

diacetyl

menadione

caldariellaquinone

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol

6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol

caldariellaquinol

adenine

guanine

AMP

GMP

XMP

IMP

ATP

GTP

ITP

ADP

GDP

IDP

dGDP

dADP

dIDP

dGTP

dATP

dITP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyguanosine

tetrahydromethanopterin

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

6-carboxy-5,6,7,8-tetrahydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropteroate

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

7,8-dihydrofolate monoglutamate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

thio-molybdenum cofactor

MoO₂-molybdopterin cofactor

reduced riboflavin

FMNH₂

riboflavin

FMN

6,7-dimethyl-8-(1-D-ribityl)lumazine

hydantoin

precorrin-2

precorrin-1

precorrin-8x

precorrin-3A

preQ₁

isoguanine

thymine

uracil

UDP

UTP

dUTP

CTP

dCTP

dUDP

CDP

dCDP

dTTP

dTDP

dCMP

dUMP

dipicolinate

5,6-dihydrothymine

5,6-dihydrouracil

dTMP

UMP

CMP

cytidine

uridine

thymidine

2'-deoxyuridine

2'-deoxycytidine

coenzyme A

coenzyme M

methyl-CoM

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-AMP

pppGpp

1-(5-phospho-β-D-ribosyl)-ATP

ppGpp

8-oxo-GTP

8-oxo-dGTP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

5-hydroxy-CMP

5-hydroxy-CTP

2-hydroxy-dATP

cyclic di-3',5'-guanylate

two adjacent thymidines in DNA

(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA)

NADP⁺

NAD⁺

NADPH

NADH

glycine betaine

(S)-NADHX

(R)-NADHX

thiamine

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

ethene

(indol-3-yl)acetate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

trans-dienelactone

cis-dienelactone

malonyl-CoA

acetyl-CoA

isobutanoyl-CoA

3'-dephospho-CoA

2-methylacetoacetyl-CoA

methylacrylyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

(E)-2-methylcrotonoyl-CoA

3-hydroxyisovaleryl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

succinyl-CoA

(E)-glutaconyl-CoA

(R)-2-hydroxyglutaryl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

(2R)-ethylmalonyl-CoA

(2S)-ethylmalonyl-CoA

4-hydroxybutanoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

phenylacetyl-CoA

CoA-disulfide

2-methylbutanoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

4-methyl-3-oxoadipyl-CoA

3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

decanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

octanoyl-CoA

propanoyl-CoA

butanoyl-CoA

(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA

(Z)-15-tetracosenoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA

(3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA

phytenoyl-CoA

(2E)-oct-2-enoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

3-sulfopyruvate

L-cysteate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

glutathione

methanethiol

(2R)-phospho-3-sulfolactate

choline

agmatine

putrescine

spermidine

4-aminobutanal

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

hydroxyl radical