an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

4-methylbenzyl alcohol

3-methylbenzaldehyde

3-methylbenzyl alcohol

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

L-selenocystathionine

3-phosphooxypyruvate

DNA without lesion

5-oxo-L-proline

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

2-dehydropantoate

preuroporphyrinogen

porphobilinogen

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

histidinol

S-Inosyl-L-homocysteine

urocanate

4-imidazolone-5-propanoate

formamide

4-methyl-3-oxoadipate

4-methyl-3-oxoadipate-enol-lactone

prenyl diphosphate

methyl-1,4-benzoquinol

(2S)-lactyl-2-diphospho-5'-guanosine

7,8-didemethyl-8-hydroxy-5-deazariboflavin

histidinal

oxalate

methylsalicylate

N²-succinylglutamate

3-oxopropanoate

(S)-dihydroorotate

3-hydroxypropanal

4-amino-4-deoxychorismate

N-(5-phosphoribosyl)-anthranilate

oxalosuccinate

4-prenylphlorisobutyrophenone

thiamine diphosphate

thiamine phosphate

2-dehydro-3-deoxy-D-galactonate

tartronate semialdehyde

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

4-phosphooxy-L-threonine

3-amino-1-hydroxyacetone 1-phosphate

5-carboxymethyl-2-hydroxymuconate

D-xylonate

(S)-2-amino-6-oxohexanoate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

2-dehydro-3-deoxy-D-galactonate 6-phosphate

salicyl alcohol

succinate semialdehyde

2-methyl-1,4-benzoquinone

2-dehydro-3-deoxy-D-arabinonate

xanthine

(R)-4'-phosphopantothenate

(R)-4-phosphopantoate

autoinducer 2

S-ribosyl-L-homocysteine

O-acetyl-L-serine

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

α-D-glucosamine 1-phosphate

γ-L-glutamyl 5-phosphate

carboxyphosphate

S-adenosyl 3-(methylsulfanyl)propylamine

(R)-mevalonate

5,6-dimethylbenzimidazole

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

nicotinate adenine dinucleotide

(R)-5-phosphomevalonate

dialurate

mesaconate

dihydroxyacetone

4-oxoglutaramate

1-piperideine 6-carboxylate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

ammonia

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

carbon monoxide

arsenite

CO₂

coproporphyrinogen III

H₂O

(4,5-dihydro-5-oxofuran-2-yl)-acetate

squalene

presqualene diphosphate

glycolate

(4Z)-2-oxohept-4-enedioate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

L-histidinol phosphate

imidazole acetol-phosphate

glycerone phosphate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

phosphoenolpyruvate

isochorismate

carbamoyl phosphate

isopentenyl diphosphate

(R)-mevalonate diphosphate

3-hydroxyanthranilate

anthranilate

β-D-ribosylnicotinate

β-nicotinate D-ribonucleotide

carbonic acid

prephenate

shikimate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

2-succinylbenzoate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

1,4-dihydroxy-2-naphthoate

4-chloro-2-methyl-cis,cis-muconate

4-methylmuconolactone

2-chloro-4-methyl-cis,cis-muconate

(2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate

2-dehydro-3-deoxy-D-gluconate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

(2R,3S)-3-methylmalate

citraconate

2-isopropylmaleate

(2S)-2-isopropylmalate

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-acetolactate

3-methyl-2-oxobutanoate

2-phosphoglycolate

hydroxypyruvate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

urea

L-canavanine

ethanolamine

oxaloacetate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

4'-phosphopantetheine

7-carboxy-7-deazaguanine

hydrogen peroxide

creatinine

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

(R)-1-aminopropan-2-ol

(R)-1-amino-2-propanol O-2-phosphate

α-ribazole 5'-phosphate

α-ribazole

canavaninosuccinate

O-ureido-L-homoserine

L-arginino-succinate

(lipoyl)adenylate

citrate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

2-dehydro-3-deoxy-D-gluconate 6-phosphate

acetoacetate

4-fumaryl-acetoacetate

(R)-mandelate

(S)-mandelate

4-hydroxy-2-nonenal

5-deoxy-α-ribose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

S-methyl-5'-thioadenosine

4-aminobutanoate

3-dehydroshikimate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(S)-3-methyl-2-oxopentanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

N-succinyl-2-amino-6-ketopimelate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-L,L-2,6-diaminopimelate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(R)-4'-phosphopantothenoyl-L-cysteine

D-erythro-imidazole-glycerol-phosphate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

orotidine 5'-phosphate

L-cysteinylglycine

γ-L-glutamyl-L-cysteine

hypoglycin B

carbamate

L-kynurenine

L-citrulline

L-tyrosine

L-histidine

L-cysteine

L-methionine

L-proline

L-glutamate

L-aspartate

L-alanine

L-isoleucine

L-threonine

L-arginine

L-serine

L-phenylalanine

glycine

L-tryptophan

L-glutamine

L-asparagine

L-valine

L-leucine

L-lysine

L-homocysteine

L-homoserine

S-adenosyl-L-homocysteine

L-glutamate-5-semialdehyde

hypoglycin A

S-adenosyl-L-methionine

L-ornithine

L-canaline

O-phospho-L-homoserine

L-aspartate 4-semialdehyde

meso-diaminopimelate

seleno-L-homocysteine

L-aspartyl-4-phosphate

L-saccharopine

O-acetyl-L-homoserine

3-hydroxy-L-kynurenine

formyl-L-isoglutamine

N-acetyl-L-ornithine

N-acetyl-L-aspartate

N-acetyl-L-citrulline

N-formimino-L-glutamate

N-acetyl-L-glutamate

sarcosine

N-carbamoyl-L-aspartate

(2S, 3S)-3-methylaspartate

L-threonine 3-O-phosphate

3-phospho-L-serine

L-cystathionine

L-isoglutamine

L,L-diaminopimelate

D-proline

N-carbamoylsarcosine

creatine

β-alanine

salicylate

4-aminobenzoate

acetate

(R)-pantoate

5-chloro-5-deoxy-D-ribonate

D-mannonate

D-gluconate

orotate

(S)-1-pyrroline-5-carboxylate

pristanate

palmitate

stearate

octanoate

laurate

7-hydroxylaurate

decanoate

(15Z)-tetracosenoate

oleate

phytenate

(12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoate

(12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoate

(9Z,15Z)-12,13-dihydroxyoctadeca-9,15-dienoate

(9Z,12Z)-15,16-dihydroxyoctadeca-9,12-dienoate

(9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate

(9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate

linoleate

α-linolenate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

(R)-3-hydroxybutanoate

(S)-lactate

(R)-lactate

(R)-glycerate

pyruvate

formate

propanoate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxoglutarate

2-oxobutanoate

glyoxylate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

3-oxoadipate

cis-aconitate

D-threo-isocitrate

chorismate

3-methyl-cis,cis-muconate

α,ω-9Z-octadecenedioate

maleate

fumarate

succinate

(S)-malate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

3-heptaprenyl-4-hydroxybenzoate

3-nonaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-hexaprenyl-4-hydroxybenzoate

geranyl diphosphate

geranylgeranyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-heptaprenyl diphosphate

(2E,6E)-farnesyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

all-trans-retinyl palmitate

all-trans-retinol

methylglyoxal

caldariellaquinone

diacetyl

α-D-galactopyranose

D-glyceraldehyde

4-methylbenzaldehyde

benzaldehyde

formaldehyde

1-propanal

acetaldehyde

benzyl alcohol

6-hydroxy-2-cyclohexen-one-carboxylate

4-hydroxybenzoate

urate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

catechol

caldariellaquinol

demethylmenaquinol-8

3-chlorobenzaldehyde

3-chlorobenzyl alcohol

phenol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

AMP

XMP

IMP

GMP

ITP

ATP

GTP

IDP

ADP

GDP

dIDP

dADP

dGDP

dITP

dGTP

dATP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyinosine

2'-deoxyadenosine

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

7,8-dihydroneopterin 3'-triphosphate

5,10-methylene-tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

cytidylyl molybdenum cofactor

bis(guanylyl molybdopterin) cofactor

bis(molybdenum cofactor)

adenylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

FMNH₂

riboflavin

FMN

FAD

thymine

uracil

cytidine 2',3'-cyclic monophosphate

uridine 2'3'-cyclic monophosphate

UDP

dUDP

CDP

dCDP

dCMP

cytidine-3'-monophosphate

uridine 3'-monophosphate

dTDP

dUMP

dTMP

CTP

UTP

dUTP

dCTP

dTTP

CMP

UMP

cytidine

uridine

thymidine

2'-deoxyuridine

2'-deoxycytidine

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-α-D-glucose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactose

UDP-α-D-glucose

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-mannosaminuronate

cob(I)alamin

adenosylcobalamin

sirohydrochlorin

cobyrinate

precorrin-2

precorrin-1

coenzyme A

(R)-lipoate

oxidized coenzyme F₄₂₀-0

adenosine 2',3'-cyclic monophosphate

guanosine 2',3'-cyclic monophosphate

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

guanosine 3'-monophosphate

adenosine 3'-monophosphate

5'-deoxyadenosine

cyclic-AMP

adenylo-succinate

ADP ribose 1''-phosphate

ADP ribose 1'',2''-cyclic phosphate

ADP-D-ribose

GDP-α-D-mannose

P¹,P⁴-bis(5'-adenosyl) tetraphosphate

NAD⁺

NADP⁺

NADH

NADPH

β-nicotinamide D-ribonucleotide

5-hydroxy-CMP

5-hydroxy-CTP

cyclic di-3',5'-guanylate

ferrichrome

glycine betaine

(S)-NADHX

(R)-NADHX

sn-glycero-3-phosphoethanolamine

glycerophosphoserine

glycerophosphoglycerol

(S)-propane-1,2-diol

myo-inositol

1D-myo-inositol 3-monophosphate

1D-myo-inositol 1-monophosphate

glycerol

L-iditol

D-sorbitol

ethanol

methanol

(indol-3-yl)acetate

phenylacetate

methyl (indol-3-yl)acetate

(+)-7-epi-jasmonate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

isobutanoyl-CoA

(+)-7-epi-jasmonoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

oxalyl-CoA

formyl-CoA

2-methylacetoacetyl-CoA

phenylacetyl-CoA

(2R,3S)-β-methylmalyl-CoA

2-methylfumaryl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

succinyl-CoA

acetyl-CoA

(2R)-ethylmalonyl-CoA

(2S)-ethylmalonyl-CoA

3'-dephospho-CoA

phytenoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

octanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

decanoyl-CoA

propanoyl-CoA

pristanoyl-CoA

(Z)-15-tetracosenoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

D-glucono-1,5-lactone

2-chloro-5-methyl-dienelactone

cis-dienelactone

2-methyl-trans-dienelactone

2-methyl-cis-dienelactone

2-chloro-3-methyl-dienelactone

3-chloro-2-methyl-dienelactone

5-chloro-trans-dienelactone

5-chloro-2-methyl-dienelactone

(+)-2-chloromuconolactone

(+)-5-chloromuconolactone

2-(2-chloro-4-methyl-5-oxofuran-2-yl)acetate

2-chloro-4-methyl-cis-dienelactone

2,5-dichloro-3-methyl-muconolactone

3,6-dichloro-3a-methyl-dihydro-3H-furo[3,2-b]furan-2,5-dione

3,5-dichloro-2-methyl-muconolactone

5-chloro-3-methyl-cis-dienelactone

2,5-dichloro-4-methyl-muconolactone

S-(hydroxymethyl)glutathione

glutathione

(R)-S-lactoylglutathione

(2R)-phospho-3-sulfolactate

3-sulfopyruvate

L-cysteate

(2R)-3-sulfolactate

methanethiol

thiocyanate

superoxide

phlorisovalerophenone

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine

daunorubicin

deoxycohumulone

deoxyhumulone

4-prenylphlorisovalerophenone

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

agmatine

spermidine

dehydrospermidine

spermine

putrescine

2-aminoprop-2-enoate

2-iminopropanoate

(2Z)-2-aminobut-2-enoate

D-galactonate

1-(β-D ribofuranosyl)nicotinamide

1-O-acetyl-α-maltose

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

α-D-mannose 1-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

D-ribulose-1,5-bisphosphate

β-D-fructofuranose

keto-D-fructose

keto-L-sorbose

N-acetyl-β-D-mannosamine

N-acetyl-β-D-glucosamine

sucrose

stachyose

raffinose

nitrite

sulfate

hydrogensulfite

nitrate

hydrogencarbonate

sulfite

thiosulfate

selenate

chloride

phosphonate

phosphate

diphosphate

triphosphate

Fe³⁺

Fe²⁺

Mg²⁺

Hg²⁺

Mo²⁺

Cd²⁺

Pb²⁺

Cu²⁺

Co²⁺

Zn²⁺

ammonium

H⁺

2-chloroacetate

2-chloro-cis,cis-muconate

2,3-dichloro-5-methyl-muconate

2-chloro-2-(2-chloro-4-methyl-5-oxofuran-2-yl)acetate

3,5-dichloro-2-methyl-muconate

2-(2,4-dichloro-5-oxofuran-2-yl)propanoate

2,5-dichloro-3-methyl-muconate

2,3-dichloro-cis,cis-muconate

2-chloro-2-(2-chloro-5-oxofuran-2-yl)acetate

3-chloro-cis,cis-muconate

2,4-dinitrophenyl-S-glutathione

1-chloro-2,4-dinitrobenzene

hydrogen cyanide

preQ₀

(R)-4-hydroxymandelate

(S)-4-hydroxymandelate

(R)-citramalate

(S)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

2-iminobutanoate

Hg⁰

oxygen

hydrogen sulfide

uroporphyrinogen-III

protoporphyrin IX

Mg-protoporphyrin

uroporphyrinogen-I

protoporphyrinogen IX

siroheme

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobinamide

cob(I)inamide

cob(I)yrinate a,c-diamide

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

adenosylcobinamide-GDP

adenosyl-cobinamide phosphate

adenosylcobalamin 5'-phosphate

DNA with lesion

(glutathion-S-yl)-4-hydroxy-2-nonenal