an oxidized electron donor
a reduced electron donor
a deaminated amino group acceptor
an aminated amino group acceptor
Charged-LEU-tRNAs
LEU-tRNAs
a 2-oxo acid
an amino acid
an acyl-CoA
a carboxylate
an oxidized ferredoxin [iron-sulfur] cluster
a reduced ferredoxin [iron-sulfur] cluster
NAD(P)H
NAD(P)+
an L-tyrosyl-[tRNAtyr]
a tRNAtyr
(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde
4α,14α-dimethyl-porifersta-8,25(27)-dienol
2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate
4-methylcyclohex-1,5-diene-1-carbonyl-CoA
isoshowacene
2-hydroxyhexadecanal
16-sinapoyloxypalmitate
3-methylquinolin-2-ol
(22R)-hydroxycholesterol
N-(2-methylpropyl)hydroxylamine
chloroeremomycin
3-hydroxy-3-methylbutanoate
2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone
2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone
2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone
rhamnosyl tetracyclic spinosyn pseudoaglycone
rhamnosyl tricyclic spinosyn pseudoaglycone
spinosyn tricyclic macrolactone
11-dehydro-15-oxo spinosyn macrolactone
15-oxo spinosyn macrolactone
spinosyn macrolactone
diethylamine N-oxide
triethylamine N-oxide
UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate
nitroxyl
trans,octacis-decaprenylphospho-β-D-arabinofuranose
1,3-dihydro-2H-imidazol-2-one
2-phenylethyl β-D-glucopyranoside
formyl hopane
ribosyl hopane
adenosyl hopane
(2Z)-2-hydroxypenta-2,4-dienoate
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
(2Z)-2,4-dihydroxypent-2-enoate
(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA
(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA
(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA
(+)-3'-hydroxylarreatricin
(+)-larreatricin
2-trans,4-trans-xanthoxin
L-arginino-succinate
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
2-oxepin-2(3H)-ylideneacetyl-CoA
3-oxo-5,6-didehydrosuberyl-CoA
3-oxo-5,6-didehydrosuberyl-CoA semialdehyde
4-amino-2-methyl-5-pyrimidinemethanol
L-gulono-1,4-lactone
L-xylo-hex-3-ulono-1,4-lactone
α-D-galacturonate 1-phosphate
H2O
urocanate
4-imidazolone-5-propanoate
dihydroxyacetone
anthranilate
isopentenyl diphosphate
O-acetyl-L-serine
2-amino-2-deoxy-D-gluconate 6-phosphate
glycerone phosphate
N-acetyl-D-galactosamine 6-phosphate
D-galactosamine-6-phosphate
N-acetyl-D-muramate 6-phosphate
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine
(E)-4-coumaroyl-CoA
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA
2,3-didehydroadipyl-CoA
CO2
hydrogen selenide
3-dehydroshikimate
shikimate
carbamoyl phosphate
4'-phosphopantetheine
hydrogen peroxide
γ-L-glutamyl 5-phosphate
phosphoenolpyruvate
nicotinate adenine dinucleotide
acetoacetate
5-enolpyruvoyl-shikimate 3-phosphate
shikimate 3-phosphate
4-methylumbelliferyl glucoside
4-hydroxybenzaldehyde
scopolin
cis-coumarinic acid-β-D-glucoside
O-D-alanyl-poly(ribitol phosphate)
poly(ribitol phosphate)
(R)-4'-phosphopantothenate
(R)-pantothenate
(R)-4'-phosphopantothenoyl-L-cysteine
oxaloacetate
2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA
citrate
xanthine
thiamine phosphate
coproporphyrinogen III
S-acetyldihydrolipoamide
dihydrolipoamide
N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate
prenyl diphosphate
(S)-3-methyl-2-oxopentanoate
4-methyl-2-oxopentanoate
3-methyl-2-oxobutanoate
(S)-dihydroorotate
4-guanidinobutanoate
4-guanidinobutyramide
acrylate
acrylamide
(indol-3-yl)acetamide
propionamide
orotidine 5'-phosphate
2-dehydropantoate
glutathione disulfide
3-dehydroquinate
2-dehydro-3-deoxy-D-gluconate 6-phosphate
5-dehydro-D-gluconate
salicyl alcohol
S-ribosyl-L-homocysteine
formamide
4-amino-4-deoxychorismate
β-nicotinate D-ribonucleotide
DNA without lesion
pyrazine-2-carboxylate
quinolinate
3-keto-L-gulonate 6-phosphate
acetyl phosphate
5-hydroxyindole acetaldehyde
5-hydroxytryptophol
autoinducer 2
3-methoxy-4-hydroxyphenylglycolaldehyde
indole-3-glycol aldehyde
indole-3-glycol
isobutanol
3-methylbutanal
3-methylbutanol
2-methylbutanal
2-methylbutanol
2-phenylethanol
3-keto-β-D-galactose
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole
3-deoxy-D-arabino-heptulosonate 7-phosphate
5-amino-1-(5-phospho-β-D-ribosyl)imidazole
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
N1-(5-phospho-β-D-ribosyl)glycinamide
5-phospho-β-D-ribosylamine
N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide
2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine
(lipoyl)adenylate
ethanolamine
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate
succinate semialdehyde
α-D-glucosamine 1-phosphate
arsenite
(R)-mevalonate diphosphate
(R)-5-phosphomevalonate
(R)-mevalonate
β-D-ribosylnicotinate
2-dehydro-3-deoxy-D-gluconate
2-oleoylglycerol
L-selenocystathionine
1,6-anhydro-N-acetyl-β-muramate
4-aminobutanoate
D-gluconate 6-phosphate
6-phospho D-glucono-1,5-lactone
carbon monoxide
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one
(R)-2,3-dihydroxy-3-methylpentanoate
(S)-2-aceto-2-hydroxybutanoate
2-amino-3-carboxymuconate-6-semialdehyde
L-dehydro-ascorbate
4-oxoglutaramate
ammonia
5-hydroxyindole thiazolidine carboxylate
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one
enol-phenylpyruvate
cyclic-2,3-O-oxalyl-L-threonate
dehydroascorbate (bicyclic form)
(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran
cyclic- 3,4-O-oxalyl-L-threonate
2,3-dioxo-L-gulonate
2-carboxy-L-xylonolactone
2-carboxy-L-threo-pentonate
(2E,6E)-farnesyl diphosphate
(S)-3-hydroxy-isobutanoate
5,10-methenyltetrahydrofolate mono-L-glutamate
(R)-methylmalonate-semialdehyde
(S)-methylmalonate-semialdehyde
1-oleoyl-2-lyso-glycerone phosphate
N-acetyl-D-mannosamine 6-phosphate
α-D-glucosamine 6-phosphate
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose
3-phospho-D-glyceroyl-phosphate
2,3-diphospho-D-glycerate
3-phospho-D-glycerate
2-phospho-D-glycerate
sn-glycerol 3-phosphate
hydrogen sulfide
oxygen
protochlorophyllide a
chlorophyllide a
3,8-divinyl protochlorophyllide a
protoporphyrinogen IX
protoporphyrin IX
uroporphyrinogen-III
Mg-protoporphyrin
magnesium-protoporphyrin IX 13-monomethyl ester
protoheme
hydrogen cyanide
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester
phenylacetate
DNA with lesion
2-iminopropanoate
2-iminobutanoate
2-iminosuccinate
glycyl-L-methionine
L-alanyl-L-aspartate
L-alanyl-L-glutamine
L-alanyl-glycine
L-alanyl-L-histidine
L-alanyl-L-leucine
L-alanyl-L-threonine
L-alanyl-L-glutamate
glycyl-L-asparagine
glycyl-L-glutamine
glycyl-L-glutamate
glycyl-L-aspartate
glycyl-L-proline
L-cysteinylglycine
L-alanyl-D-glutamate
D-alanyl-D-alanine
L-methionyl-L-alanine dipeptide
L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine
L-alanyl-γ-D-glutamyl-meso-diaminopimelate
L-histidine
L-arginine
L-lysine
L-glutamate
D-glutamate
L-serine
L-glutamine
L-proline
L-alanine
glycine
L-leucine
β-alanine
(S)-3-amino-2-methylpropanoate
L-methionine
L-selenocysteine
L-valine
L-isoleucine
L-phenylalanine
L-cysteine
L-aspartate
L-ornithine
L-asparagine
L-threonine
L-tyrosine
L-cystathionine
L-isoglutamine
N-carbamoyl-L-aspartate
formyl-L-isoglutamine
N-formimino-L-glutamate
L-citrulline
S-adenosyl-L-homocysteine
S-adenosyl-L-methionine
S-sulfo-L-cysteine
L-glutamate-5-semialdehyde
L-homocysteine
meso-diaminopimelate
seleno-L-homocysteine
D-alanine
D-aspartate
AMP
ATP
XMP
IMP
dATP
GTP
dGTP
ADP
GDP
GMP
dADP
dGDP
2'-deoxyadenosine
2'-deoxyguanosine
hypoxanthine
2'-deoxyinosine
5-chloro-5-deoxyribose 1-phosphate
5'-chloro-5'-deoxyadenosine
pppGpp
5'-deoxyadenosine
adenylo-succinate
dGMP
ppGpp
8-oxo-dGMP
8-oxo-dGTP
8-oxo-GMP
8-oxo-GTP
dAMP
ADP-D-ribose
GDP-α-D-glucose
GDP-α-D-mannose
dTDP-α-D-glucose
dTDP-4-dehydro-β-L-rhamnose
dTDP-β-L-rhamnose
UDP-α-D-galactofuranose
UDP-α-D-galacturonate
UDP-α-D-glucose
UDP-α-D-glucuronate
UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate
UDP-N-acetyl-α-D-muramoyl-L-alanine
UDP-N-acetyl-α-D-glucosamine-enolpyruvate
UDP-N-acetyl-α-D-muramate
UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine
UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine
UDP-α-D-galactose
UDP-N-acetyl-α-D-glucosamine
UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate
UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine
UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine
adenine
guanine
uracil
thymine
preQ1
NAD+
NADP+
NADH
NADPH
dUMP
dTMP
dCMP
dCDP
dUDP
dTDP
dCTP
dUTP
dTTP
UDP
CDP
β-nicotinamide D-ribonucleotide
UTP
CTP
CMP
UMP
2'-deoxyuridine
2'-deoxycytidine
thymidine
adenosine
inosine
guanosine
xanthosine
cytidine
uridine
5'-deoxy-5'-fluoroadenosine
L-gulonate
aldehydo-L-galactonate
D-gluconate
L-idonate
1-(β-D ribofuranosyl)nicotinamide
decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide
3'-ketolactose
lotaustralin
taxiphyllin
linamarin
linustatin
neolinustatin
arbutin-6-phosphate
salicin 6-phosphate
methyl β-D-glucoside 6-phosphate
D-erythrose 4-phosphate
D-sedoheptulose 7-phosphate
5-phospho-α-D-ribose 1-diphosphate
α-D-glucopyranose 1-phosphate
α-D-mannose 1-phosphate
N-acetyl-α-D-glucosamine 1-phosphate
β-D-fructofuranose 1-phosphate
β-D-glucopyranose 1-phosphate
α-D-galactose 6-phosphate
β-D-galactose 6-phosphate
D-tagatofuranose 6-phosphate
L-ascorbate 6-phosphate
β-D-fructose 1,6-bisphosphate
β-D-fructofuranose 6-phosphate
D-tagatofuranose 1,6-bisphosphate
D-fructose 6-phosphate
β-D-glucose 6-phosphate
α-D-glucose 6-phosphate
α-D-mannopyranose 6-phosphate
β-D-mannopyranose 6-phosphate
α-D-ribose-1-phosphate
5-fluoro-5-deoxy-D-ribose 1-phosphate
2-deoxy-α-D-ribose 1-phosphate
D-xylulose 5-phosphate
L-xylulose 5-phosphate
D-ribulose 5-phosphate
L-ribulose 5-phosphate
D-glyceraldehyde 3-phosphate
sucrose 6G-phosphate
N,N'-diacetylchitobiose 6'-phosphate
N-monoacetylchitobiose 6'-phosphate
sucrose 6F-phosphate
α-lactose 6'-phosphate
β-D-cellobiose 6'-phosphate
undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine
a peptidoglycan dimer (mycobacteria)
decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)
undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine
a peptidoglycan dimer (E. faeciums)
a peptidoglycan dimer (S. aureus)
a peptidoglycan dimer (E. faecium, tetrapeptide)
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala
ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine
a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)
a peptidoglycan dimer (meso-diaminopimelate containing)
a peptidoglycan with L,D cross-links (mycobacteria)
a peptidoglycan with D,D cross-links (mycobacteria)
a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)
a peptidoglycan with D,D cross-link (S. aureus)
a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)
β-D-fructofuranose
glycolaldehyde
aldehydo-D-ribose
β-D-ribofuranose
α-D-ribofuranose
β-D-galactopyranose
β-D-glucopyranose
α-D-glucopyranose
D-glyceraldehyde
L-glyceraldehyde
N-acetylmuramate
N-acetyl-α-D-muramoyl-L-alanine(1-)
N-acetyl-β-D-mannosamine
N-acetyl-β-D-glucosamine
N-acetyl-β-neuraminate
glycerol
galactitol
XXXG xyloglucan oligosaccharide
β-D-cellobiose
maltotriose
sucrose
allolactose
α-lactose
maltotetraose
maltopentaose
maltohexaose
maltoheptaose
XLLG xyloglucan oligosaccharide
XLXG xyloglucan oligosaccharide
XXLG xyloglucan oligosaccharide
aldehydo-D-galacturonate
4-methylumbelliferone
scopoletin
coumarin
trans,octacis-decaprenyl phosphate
mono-trans,octa-cis-decaprenyl diphosphate
geranyl diphosphate
1,2-dibutyrin
tributyrin
di-trans,octa-cis-undecaprenyl phosphate
di-trans,octa-cis-undecaprenyl diphosphate
dioleoyl phosphatidate
1-oleoyl-sn-glycerol 3-phosphate
1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate
myo-inositol
1D-myo-inositol 2-monophosphate
1D-myo-inositol 6-monophosphate
1D-myo-inositol 5-monophosphate
1D-myo-inositol 4-monophosphate
1D-myo-inositol 3-monophosphate
1D-myo-inositol 1-monophosphate
hydroquinone
3,4-dihydroxyphenylglycolaldehyde
3,4-dihydroxyphenylglycol
ethanol
propan-1-ol
phytol
butan-1-ol
methanol
methylglyoxal
(4-hydroxyphenyl)acetaldehyde
phenylacetaldehyde
phytenal
acetaldehyde
formaldehyde
1-propanal
isobutanal
butan-1-al
pyruvate
2-oxoglutarate
2-oxobutanoate
3-phenyl-2-oxopropanoate
4-aminobenzoate
acetate
orotate
(R)-pantoate
aldehydo-D-glucuronate
(S)-1-pyrroline-5-carboxylate
butanoate
formate
propanoate
(R)-lactate
(S)-lactate
(R)-3-hydroxybutanoate
chorismate
(3E)-2-oxohex-3-enedioate
fumarate
succinate
(S)-malate
4-tyrosol
urate
coumarinate
serotonin
N-acetyl-serotonin
3-methoxy-4-hydroxyphenylglycol
preQ0
(2R)-2-hydroxy-2-methylbutanenitrile
2-hydroxy-2-methylpropanenitrile
(7,8-dihydropterin-6-yl)methyl diphosphate
6-(hydroxymethyl)-7,8-dihydropterin
7,8-dihydroneopterin
7,8-dihydromonapterin
7,8-dihydroneopterin 3'-triphosphate
7,8-dihydroneopterin 3'-phosphate
7,8-dihydropteroate
7,8-dihydrofolate monoglutamate
5,6,7,8-tetrahydrofolate
tetrahydropteroyl tri-L-glutamate
(6S)-5-formyl-tetrahydrofolate mono-L-glutamate
5-methyltetrahydropteroyl tri-L-glutamate
5-methyltetrahydropteroyl mono-L-glutamate
10-formyl-tetrahydrofolate mono-L-glutamate
5,10-methylenetetrahydropteroyl mono-L-glutamate
FAD
FMN
riboflavin
FADH2
L-ascorbate
thiamine
nicotinate
nicotinamide
pyridoxine 5'-phosphate
pyridoxine
pyridoxamine 5'-phosphate
pyridoxamine
pyridoxal 5'-phosphate
pyridoxal
coenzyme A
(R)-lipoate
(R)-NADHX
(S)-NADHX
D-glucono-1,5-lactone
L-galactono-1,4-lactone
acetyl-CoA
methylacrylyl-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA
(3S)-hydroxyadipyl-CoA
(E)-2-methylcrotonoyl-CoA
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA
3-hydroxyisovaleryl-CoA
malonyl-CoA
(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA
(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA
2-methylacetoacetyl-CoA
3'-dephospho-CoA
succinyl-CoA
(S)-3-hydroxy-3-methylglutaryl-CoA
phenylacetyl-CoA
isobutanoyl-CoA
2-methylbutanoyl-CoA
(S)-3-hydroxy-isobutanoyl-CoA
oleoyl-CoA
3-oxoadipyl-CoA
3-oxopentanoyl-CoA
acetoacetyl-CoA
hexadecanedioyl-CoA
propanoyl-CoA
butanoyl-CoA
(3R)-3-hydroxybutanoyl-CoA
(S)-3-hydroxybutanoyl-CoA
(S)-3-hydroxydecanoyl-CoA
(S)-3-hydroxyoctanoyl-CoA
(2E)-dec-2-enoyl-CoA
(2E)-oct-2-enoyl-CoA
crotonyl-CoA
(S)-methylmalonyl-CoA
(R)-methylmalonyl-CoA
5-amino-4-imidazolecarboxyamide
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
pyrazinamide
acetamide
(indol-3-yl)acetate
glycerophosphoserine
glycerophosphoglycerol
sn-glycero-3-phosphoethanolamine
2-aminoprop-2-enoate
(2Z)-2-aminobut-2-enoate
trimethyl sulfonium
thiosulfate
hydrogencarbonate
superoxide
phosphate
diphosphate
Mg2+
Fe2+
Ca2+
Na+
H+
ammonium
S-(hydroxymethyl)glutathione
3-(methylsulfanyl)propanal
methionol
dimethyl sulfide
glutathione
(R)-S-lactoylglutathione
3-sulfopyruvate
L-cysteate
hydroxyl radical
monodehydroascorbate radical