an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

S-ribosyl-L-homocysteine

autoinducer 2

(2R,3S)-3-methylmalate

citraconate

4-amino-2-methyl-5-pyrimidinemethanol

2-oxoadipate

7-mercaptoheptanoylthreonine

7-mercaptoheptanoate

7-oxoheptanoate

2-oxosuberate

cis-(homo)₃aconitate

2-oxopimelate

cis-(homo)₂aconitate

2-(α-hydroxyethyl)thiamine diphosphate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

(R)-mevalonate diphosphate

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

oxalosuccinate

carbon monoxide

dialurate

1,4-dihydroxy-2-naphthoate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

pseudouridine 5'-phosphate

4-amino-4-deoxychorismate

isopentenyl phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

5-hydroxytryptophol

5-hydroxyindole acetaldehyde

3-methoxy-4-hydroxyphenylglycolaldehyde

indole-3-glycol

indole-3-glycol aldehyde

isobutanol

3-methylbutanol

3-methylbutanal

2-methylbutanol

2-methylbutanal

2-phenylethanol

DNA without lesion

creatinine

2-oleoylglycerol

hexulose 6-phosphate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

urea

coenzyme F₃₉₀-A

itaconate

(2S)-lactyl-2-diphospho-5'-guanosine

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

5,6-dimethylbenzimidazole

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

coproporphyrinogen III

CDP-glycerol

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4Z)-2-oxohept-4-enedioate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

N-(5-phosphoribosyl)-anthranilate

anthranilate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

α-D-glucosamine 1-phosphate

L-histidinol phosphate

N-carbamoylputrescine

quinolinate

3-phosphooxypyruvate

(R)-5-phosphomevalonate

prenyl diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

5-aminolevulinate

isopentenyl diphosphate

(R)-4'-phosphopantothenate

histidinal

histidinol

2-C-methyl-D-erythritol 4-phosphate

3-dehydroquinate

(R)-mevalonate

methanophenazine

dihydromethanophenazine

5-amino-6-(D-ribitylamino)uracil

(R)-pantothenate

3-dehydroshikimate

2-dehydropantoate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

nicotinate adenine dinucleotide

L-canavanine

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5-enolpyruvoyl-shikimate 3-phosphate

carbonic acid

shikimate

shikimate 3-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

porphobilinogen

preuroporphyrinogen

orotidine 5'-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

(S)-4-amino-5-oxopentanoate

2-phosphoglycolate

glycolate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

oxaloacetate

α-ribazole

α-ribazole 5'-phosphate

(S)-dihydroorotate

coenzyme B

CoB-CoM heterodisulfide

hydrogen peroxide

glutathione disulfide

prephenate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

pimelate

pimeloyl-CoA

H₂

phosphoenolpyruvate

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

dethiobiotin

citrate

hydrogen selenide

O-acetyl-L-serine

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

4-methyl-2-oxopentanoate

(S)-2-aceto-2-hydroxybutanoate

2-carboxy-L-threo-pentonate

(S)-2-acetolactate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dehydroascorbate (bicyclic form)

carbamoyl phosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

5-hydroxyindole thiazolidine carboxylate

ammonia

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

H₂O

L-dehydro-ascorbate

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

CO₂

thiamine phosphate

thiamine diphosphate

glycerone phosphate

(R)-1-amino-2-propanol O-2-phosphate

(R)-1-aminopropan-2-ol

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

(2E,6E)-farnesyl diphosphate

pristanate

1-oleoyl-2-lyso-glycerone phosphate

CMP-N-acetyl-β-neuraminate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

(S)-2-hydroxyglutarate

monodehydroascorbate radical

N-acetyl-β-neuraminate

dimethyl sulfide

methionol

3-(methylsulfanyl)propanal

glutathione

methanethiol

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

sulfoacetaldehyde

3-sulfopyruvate

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

trimethyl sulfonium

sulfite

thiosulfate

hydrogencarbonate

sulfide(2-)

phosphate

triphosphate

diphosphate

ammonium

H⁺

Mg²⁺

Ni²⁺

Co²⁺

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

L-homocysteine

methane

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

glycocholate

cholate

2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

glutaryl-CoA

(E)-glutaconyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

2-methylacetoacetyl-CoA

itaconyl-CoA

succinyl-CoA

3'-dephospho-CoA

malonyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

acetyl-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

decanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

L-galactono-1,4-lactone

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

caldariellaquinol

menaquinol-8

menaquinol-7

menaquinol-9

menaquinol-6

menaquinol-10

menaquinol-11

menaquinol-12

menaquinol-13

demethylmenaquinol-8

demethylmenaquinol-7

demethylmenaquinol-9

demethylmenaquinol-6

demethylmenaquinol-10

demethylmenaquinol-11

demethylmenaquinol-12

demethylmenaquinol-13

caldariellaquinone

methyl-CoM

coenzyme A

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

demethylated 7,8-dihydromethanopterin

7,8-dihydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

L-ascorbate

nicotinate

riboflavin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

(S)-1-pyrroline-5-carboxylate

adenosylcobalamin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-3A

cobalt-precorrin-2

cobalt-precorrin-3

precorrin-5

precorrin-6A

precorrin-7

precorrin-8x

precorrin-6B

precorrin-1

precorrin-2

precorrin-3B

precorrin-4

cobyrinate

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

6-(hydroxymethyl)-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

7,8-dihydropteroate

adenine

2'-deoxyadenosine

2'-deoxyguanosine

guanosine

inosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dIMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

GMP

IMP

XMP

AMP

XTP

ITP

GTP

ATP

dCMP

uracil

UDP

UTP

dUDP

dUTP

dTDP

dTTP

dCDP

dCTP

CDP

CTP

orotate

dUMP

dTMP

UDP-α-D-galacturonate

UDP-α-D-glucuronate

UDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-4-dehydro-β-L-rhamnose

dTDP-α-D-glucose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

cytidine

uridine

CMP

UMP

4-tyrosol

4-hydroxybenzoate

3-methoxy-4-hydroxyphenylglycol

(4-hydroxyphenyl)acetaldehyde

phenylacetaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

3,4-dihydroxyphenylglycol

3,4-dihydroxyphenylglycolaldehyde

4-aminobenzoate

L-2-aminoadipate

L-α-amino-ε-keto-pimelate

L-serine

creatine

β-alanine

L-proline

L-alanine

L-glutamine

L-leucine

glycine

L-glutamate

L-lysine

L-histidine

L-arginine

L-aspartate

L-cysteine

L-asparagine

L-tyrosine

L-threonine

L-tryptophan

L-phenylalanine

D-alanine

seleno-L-homocysteine

L-selenomethionine

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

3-phospho-L-serine

L-citrulline

L-valine

L-isoleucine

L-glutamate-5-semialdehyde

L-canaline

L-homoserine

O-phospho-L-homoserine

L-aspartate 4-semialdehyde

S-sulfo-L-cysteine

L-ornithine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-selenocysteine

L-methionine

L,L-diaminopimelate

(3E)-2-oxohex-3-enedioate

chorismate

succinate

fumarate

(S)-malate

(-)threo-iso(homo)₃citrate

trihomocitrate

(-)threo-iso(homo)₂citrate

dihomocitrate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

(2S,3S)-2-methylcitrate

cis-2-methylaconitate

(2R)-homocitrate

(1R,2S)-homoisocitrate

cis-homoaconitate

cis-aconitate

D-threo-isocitrate

(R)-2-hydroxybutanoate

(S)-lactate

(R)-glycerate

pyruvate

acetate

formate

propanoate

octanoate

decanoate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

phytenate

palmitate

(R)-pantoate

aldehydo-D-glucuronate

aldehydo-D-galacturonate

3-(4-hydroxyphenyl)pyruvate

2-oxoglutarate

2-oxobutanoate

diacetyl

6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone

3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone

glycolaldehyde

butan-1-al

1-propanal

isobutanal

acetaldehyde

(S)-lactaldehyde

phytenal

L-glyceraldehyde

D-glyceraldehyde

butan-1-ol

ethanol

propan-1-ol

phytol

glycerol

(3R)-linalool

(3S)-linalool

(S)-propane-1,2-diol

myo-inositol

1D-myo-inositol 3-monophosphate

1-oleoyl-sn-glycerol 3-phosphate

dioleoyl phosphatidate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

di-trans,octa-cis-undecaprenyl phosphate

geranyl diphosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

1-(β-D ribofuranosyl)nicotinamide

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

sucrose 6^F-phosphate

GDP-α-D-mannose

GDP-α-D-mannuronate

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

aldehydo-L-galactonate

L-gulonate

cyclic-AMP

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

2-iminosuccinate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

γ-L-glutamyl-L-cysteine

D-alanyl-D-alanine

DNA with lesion

cob(I)inamide

cob(I)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobalt-sirohydrochlorin

cobalt-factor III

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

Mg-protoporphyrin

adenosyl-cobinamide phosphate

adenosylcobyrate

adenosylcobinamide

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

uroporphyrinogen-I

oxygen

hydrogen sulfide

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate